Can Mild Corneal Vascularization from Contact Lenses Be Reversed? - Ophthalmology

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Is mild vascular proliferation in the perineal area reversible?


Hello, doctor.
I have been wearing colored contact lenses for a long time, which has caused corneal hypoxia and epithelial damage.
The clinic physician mentioned that there is early vascularization at the limbal region of my cornea, and that if I stop wearing contact lenses, the vessels will regress on their own.
After treatment, my symptoms have improved, and during my follow-up visit, the doctor said the vessels have indeed regressed.
However, I read on a medical website that corneal neovascularization cannot fully revert, and that even if I stop wearing contact lenses, the vessels will still persist.
I would like to ask the doctor if the mildly vascularized vessels at the corneal limbus will disappear.

Miss Huang, 20~29 year old female. Ask Date: 2021/02/13

Dr. Gao Pilin reply Ophthalmology


Hello Ms.
Huang: The neovascularization may persist but can also regress.
Therefore, at times, it may regress, and there may be no blood within the vessels, making it undetectable.
In Taiwan, at Puzi Hospital's ophthalmology department: Monday, Tuesday, Thursday, and Friday mornings from 8:00 AM to 12:00 PM, and Wednesday afternoons from 2:00 PM to 4:30 PM.
Online responses can only serve as a reference; it is necessary to seek medical attention at a healthcare facility.
I hope to have the opportunity to serve you.
Gao Pilin

Reply Date: 2021/02/13

More Info


Mild corneal vascularization, particularly when associated with contact lens wear, can indeed be reversible, especially if the condition is caught early and appropriate measures are taken. In your case, it sounds like you have already taken the first crucial step by discontinuing the use of colored contact lenses, which can contribute to corneal hypoxia and subsequent vascularization.
Corneal vascularization, or neovascularization, occurs when new blood vessels grow into the cornea, often as a response to hypoxia or inflammation. The cornea is normally avascular (lacking blood vessels), and the presence of new blood vessels can indicate that the cornea is trying to heal itself or respond to an irritant. In your situation, the initial vascularization was likely a reaction to the prolonged wear of contact lenses, which can limit oxygen supply to the cornea and lead to complications such as corneal edema, inflammation, and even scarring.

The good news is that if the vascularization is mild and the underlying cause (in this case, the contact lens wear) is addressed, the cornea has a remarkable ability to heal. When you stop wearing contact lenses, especially those that are colored or do not allow adequate oxygen transmission, the corneal epithelium can regenerate, and the inflammatory response can subside. As a result, the newly formed blood vessels may regress over time.
Your follow-up visit indicating that the blood vessels have already begun to recede is a positive sign. This suggests that your cornea is healing and that the vascularization is indeed reversible. However, it is essential to continue monitoring your condition with your eye care professional. They can provide guidance on the appropriate time to resume contact lens wear, if at all, and recommend any necessary treatments to support corneal health.

It is also worth noting that while mild cases of corneal vascularization can resolve, more severe or chronic cases may lead to permanent changes in the corneal structure. In such instances, the blood vessels may not fully regress, leading to potential long-term effects on vision. Therefore, early intervention and adherence to your eye care provider's recommendations are crucial.

In summary, mild corneal vascularization from contact lenses can often be reversed, especially if the offending lenses are removed and proper care is taken. Your experience of seeing improvement and regression of the blood vessels is encouraging. Continue to follow up with your eye doctor, and consider discussing alternative vision correction options that are more compatible with corneal health, such as daily disposable lenses or glasses, to prevent recurrence of this issue.

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