Managing a 13cm Liver Tumor: Treatment Options for Elderly Patients - Gastroenterology and Hepatology

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13 cm liver tumor


I would like to ask about my grandmother, who is nearly 90 years old and has been experiencing itching all over her body.
She went to the hospital for examination yesterday and was found to have a 13 cm tumor on her liver.
The doctor does not recommend surgery and suggested pain management with medication.
Are there any other treatment options the doctor might suggest?

sandy, 30~39 year old female. Ask Date: 2021/02/23

Dr. Chen Shidian reply Gastroenterology and Hepatology


(Self-paid) oral targeted therapy → but there are side effects.
If the results are good/tumor shrinks → embolization therapy can be considered again.

Reply Date: 2021/02/23

More Info


Managing a 13cm liver tumor in an elderly patient, particularly one who is nearly 90 years old, presents a complex challenge. Given the patient's advanced age and potential comorbidities, such as frailty and other underlying health issues, the treatment approach must be carefully considered. The recommendation from the physician to avoid surgery and focus on pain management is not uncommon in such cases, as surgical interventions can pose significant risks for older adults.

In the case of a large liver tumor, especially one measuring 13cm, the first step is to confirm the nature of the tumor. It is crucial to determine whether it is benign (such as a hemangioma or focal nodular hyperplasia) or malignant (such as hepatocellular carcinoma). This typically involves imaging studies like CT scans or MRIs, and possibly a biopsy if the tumor's characteristics are unclear. If the tumor is confirmed to be malignant, the treatment options may include systemic therapies, targeted therapies, or palliative care.

For elderly patients, particularly those who may not tolerate aggressive treatments well, palliative care becomes a vital component of management. This approach focuses on improving the quality of life by alleviating symptoms such as pain, itching, and discomfort associated with the tumor. Medications for pain management, such as opioids or non-opioid analgesics, may be prescribed based on the patient's needs.

In addition to pain management, there are other treatment options that could be considered, depending on the tumor's characteristics and the patient's overall health. For instance, targeted therapies, such as oral medications that specifically target cancer cells, may be an option. These therapies can sometimes shrink tumors or slow their growth, potentially improving the patient's quality of life. However, it is essential to discuss the potential side effects and the patient's ability to tolerate these medications.

If the tumor is indeed malignant and the patient's condition allows, other minimally invasive procedures could be explored. For example, transarterial chemoembolization (TACE) is a procedure that can be used to treat liver tumors by delivering chemotherapy directly to the tumor while blocking its blood supply. This method can be effective for certain patients and may be considered if the patient's liver function is adequate and they are not too frail.

Another option could be radiofrequency ablation (RFA), which uses heat to destroy cancer cells. This procedure is less invasive than traditional surgery and can be performed on an outpatient basis. However, the suitability of RFA would depend on the tumor's location and size, as well as the patient's overall health.

Ultimately, the decision regarding treatment should be made collaboratively between the patient, their family, and the healthcare team, considering the patient's preferences, values, and quality of life. It is also essential to have regular follow-ups to monitor the tumor's progression and adjust the treatment plan as necessary.

In conclusion, while surgery may not be advisable for an elderly patient with a 13cm liver tumor, there are several other treatment options available, including targeted therapies, palliative care, and minimally invasive procedures. A multidisciplinary approach involving oncologists, palliative care specialists, and primary care providers is crucial in managing such complex cases effectively.

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