Can Oral A Acid and Menstrual Delay Medication Be Taken Together? - Obstetrics and Gynecology

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Oral isotretinoin + menstrual regulation medication


I have been taking oral isotretinoin for nearly two months, and I want to delay my period because I am going on a trip.
Can I take these two medications at the same time?

Miss Zhang, 30~39 year old female. Ask Date: 2021/03/10

Dr. Chen Zhiyu reply Obstetrics and Gynecology


In response to your concerns, the pharmacology and properties of these two types of medications are fundamentally different and should not conflict with each other.
They can be taken together.
Thank you for your question, and I wish you health and happiness.

Reply Date: 2021/03/10

More Info


When considering the simultaneous use of oral isotretinoin (commonly referred to as "oral A acid") and medications intended to delay menstruation, it is essential to understand the pharmacological properties of both types of medications and their potential interactions.

Oral isotretinoin is primarily used for the treatment of severe acne. It works by reducing the size and activity of sebaceous glands, leading to decreased oil production and, consequently, a reduction in acne lesions. This medication is known for its significant side effects, including teratogenic effects (causing birth defects if taken during pregnancy), dry skin, and potential liver function alterations. Due to these side effects, patients on isotretinoin are usually monitored closely by their healthcare providers.

On the other hand, medications that delay menstruation, such as hormonal contraceptives or specific progestins, work by altering the hormonal balance in the body. These medications can prevent ovulation or alter the uterine lining, thus postponing the onset of menstruation. While these medications are generally considered safe for most women, they can also have side effects, including changes in mood, weight gain, and potential blood clot risks, especially in women who smoke or have other risk factors.

Regarding the question of whether these two medications can be taken together, current literature does not indicate any direct contraindications or significant drug interactions between isotretinoin and hormonal medications used for menstrual delay. However, it is crucial to consider individual health factors and the potential for side effects. For instance, both medications can cause mood changes, and taking them together might exacerbate these effects in some individuals.

Before proceeding with the combination of these medications, it is advisable to consult with a healthcare provider. They can assess your specific health situation, including any pre-existing conditions, other medications you may be taking, and your overall health profile. This is particularly important if you have a history of hormonal imbalances, mood disorders, or other health concerns that could be affected by hormonal manipulation.

In summary, while there is no documented evidence suggesting that taking oral isotretinoin and menstrual delay medications together is unsafe, individual health considerations must be taken into account. Always consult with your healthcare provider before starting any new medication or combining treatments to ensure safety and efficacy tailored to your health needs.

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