Concerns About Using Lidocaine and Neomycin During Early Pregnancy - Obstetrics and Gynecology

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Accidentally using medication in early pregnancy?


Hello, doctor.
I was unaware that I was pregnant when I was 3 weeks along and went to a cosmetic clinic for a bikini area hair removal procedure.
I received lidocaine for anesthesia during the procedure and had neomycin applied afterward.
I am very concerned about whether this could have any effects on the fetus.

Miss Su, 40~49 year old female. Ask Date: 2021/03/11

Dr. Cai Yonglong reply Obstetrics and Gynecology


Four weeks ago should not have any impact, as the embryo had not yet implanted.

Reply Date: 2021/03/11

More Info


When it comes to the use of medications during early pregnancy, it is crucial to understand the potential risks and benefits associated with each drug. In your case, you mentioned the use of lidocaine and neomycin during a cosmetic procedure when you were unaware of your pregnancy. Let's break down the implications of these medications.

Lidocaine is a local anesthetic commonly used to numb a specific area of the body. It is classified as a Category B drug by the FDA, which means that animal reproduction studies have not shown a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. The general consensus is that lidocaine is considered safe for use during pregnancy when used appropriately and in moderation. However, it is always best to minimize exposure to any medication during the first trimester, which is a critical period for fetal development.

Neomycin, on the other hand, is an antibiotic that belongs to the aminoglycoside class. It is used topically to prevent infections. Neomycin is classified as Category D, which indicates that there is evidence of risk to the fetus based on human data, but the potential benefits may warrant its use in pregnant women despite the risks. The primary concern with neomycin is its potential to cause ototoxicity (hearing loss) in the fetus if used systemically, but topical application is generally considered to have a lower risk.

In your situation, the use of lidocaine and neomycin for a cosmetic procedure is unlikely to have caused significant harm to your developing fetus, especially since these medications were applied topically and in a controlled manner. However, it is essential to monitor your pregnancy closely and consult with your healthcare provider regarding any concerns you may have.

Potential Risks and Monitoring: While the immediate risks from lidocaine and neomycin in this context are low, it is still important to be vigilant about any unusual symptoms during your pregnancy. If you experience any signs of complications, such as severe abdominal pain, unusual bleeding, or any other concerning symptoms, you should seek medical attention promptly.

Consulting Your Healthcare Provider: It is advisable to discuss your concerns with your obstetrician or healthcare provider. They can provide personalized advice based on your medical history and the specifics of your pregnancy. They may also recommend additional monitoring or tests to ensure that everything is progressing normally.

Conclusion: Overall, while the use of lidocaine and neomycin during early pregnancy raises some concerns, the risks associated with their topical application in a controlled setting are relatively low. It is always best to err on the side of caution and consult with your healthcare provider for tailored advice and reassurance. Remember, maintaining open communication with your healthcare team is key to a healthy pregnancy.

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