How Long to Stop Birth Control and Sleep Meds Before Pregnancy? - Pharmacology

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How long does it take to conceive after stopping oral contraceptives?


If you have been taking Yaz birth control pills for 7 years and have also been using controlled substances for sleep (such as Ambien and Lunesta), and you are planning to conceive, it is generally recommended to stop taking the birth control pills at least one month before trying to get pregnant to allow your menstrual cycle to regulate.

As for the sleep medications, Ambien (zolpidem) and Lunesta (eszopiclone) typically have a half-life of about 2 to 3 hours and 6 hours, respectively.
However, it may take several days for these medications to be fully eliminated from your system.
It is advisable to consult with your healthcare provider for personalized guidance on discontinuing these medications and planning for pregnancy.

Chen Ting, 20~29 year old female. Ask Date: 2021/03/14

Dr. Zheng Shuwen reply Pharmacology


Hello, regarding your question, here is the response: According to the information reviewed, it takes about 10 days for the medication to be completely eliminated from your body.
It is recommended to stop taking oral contraceptives six months prior to planning a pregnancy to avoid issues with temporary ovulation recovery.
Additionally, ensure you get enough sleep and maintain a positive mood! You may also return to your physician to discuss any adjustments needed for controlled substances.
Wishing you all the best.
For inquiries, you can contact Taoyuan Rehabilitation Hospital at 03-3698553.

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Reply Date: 2021/03/14

More Info


When considering pregnancy after long-term use of birth control pills and sleep medications, it's essential to understand how these substances may affect fertility and the health of a future pregnancy.
1. Stopping Birth Control Pills:
Generally, it is recommended to stop taking birth control pills at least one month before trying to conceive. This allows your menstrual cycle to return to its natural rhythm, which can help in tracking ovulation and determining the best time to conceive. Some women may experience a delay in the return of their fertility, but for most, ovulation resumes within a few weeks after stopping the pill.
2. Sleep Medications:
Regarding sleep medications, such as Ambien (zolpidem) and Lunesta (eszopiclone), the timeline for discontinuation before pregnancy is less clear-cut. These medications typically have a half-life of a few hours, meaning they are eliminated from the body relatively quickly. However, it is advisable to stop using these medications at least a few weeks before trying to conceive. This allows your body to clear the drugs and helps ensure that any potential effects on fertility or fetal development are minimized.
3. Consultation with Healthcare Providers:
Before making any changes to your medication regimen, it is crucial to consult with your healthcare provider. They can provide personalized advice based on your medical history, the specific medications you are taking, and any underlying health conditions. They may also suggest alternative methods for managing sleep issues that are safer during pregnancy.

4. Potential Effects on Pregnancy:
While there is limited research on the long-term effects of birth control pills on fertility, most studies suggest that they do not have lasting impacts on a woman's ability to conceive. However, if you have been using sleep medications regularly, it is essential to discuss this with your doctor, as some medications may have implications for pregnancy and fetal development.

5. General Recommendations:
- Healthy Lifestyle: Focus on maintaining a healthy lifestyle, including a balanced diet, regular exercise, and avoiding alcohol and tobacco, which can enhance fertility and improve pregnancy outcomes.

- Prenatal Vitamins: Consider starting prenatal vitamins with folic acid at least one month before conception to support fetal development and reduce the risk of neural tube defects.

- Monitoring Health: Keep track of your menstrual cycle and ovulation patterns after stopping birth control, as this will help you identify your fertile window.

In summary, it is generally advisable to stop birth control pills at least one month before trying to conceive and to discontinue sleep medications a few weeks prior. Always consult with your healthcare provider for tailored advice and to ensure a healthy transition into pregnancy.

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