Lung Nodules: When to Worry and What to Do - Pulmonology

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White spots in the lungs?


Hello, in 2020, due to severe abdominal pain, I underwent a CT scan and PET imaging.
The physician overlooked the abdominal issue and instead mentioned a 1.3 cm nodule in my lungs, insisting on immediate intervention, which I refused because I had no discomfort.
In 2020, I consulted with a specialist who informed me of my condition—rectal cancer.
After radiation therapy for rectal cancer in 2021, a follow-up CT scan revealed that the lung nodule had increased to 1.8 cm, and again, the physician insisted on immediate intervention (still, I have no discomfort).
My question is: since I have no chest discomfort, do I need to undergo a biopsy or proceed directly to surgical removal? I feel the physician is very eager to operate.
Thank you.

Niming, 60~69 year old female. Ask Date: 2021/03/18

Dr. Yang Wenda reply Pulmonology


Hello: The enlargement of a pulmonary nodule has a significant chance of being unable to exclude malignancy (primary lung cancer or metastatic colorectal cancer to the lungs).
It is strongly recommended to perform a biopsy or surgical removal; one should not determine the need for intervention based solely on the presence or absence of symptoms!

Reply Date: 2021/03/18

More Info


Understanding lung nodules can be a source of anxiety for many patients, especially when they are discovered incidentally during imaging studies for unrelated issues. In your case, the lung nodule measuring 1.3 cm that later increased to 1.8 cm is indeed a point of concern, particularly given your history of rectal cancer.
Lung nodules, or "pulmonary nodules," are small masses of tissue in the lung that can be benign (non-cancerous) or malignant (cancerous). The size, shape, and characteristics of the nodule, along with the patient's history and risk factors, help determine the likelihood of malignancy. Generally, nodules that are larger than 1 cm, especially those that show growth over time, warrant further investigation.
In your situation, the increase in size from 1.3 cm to 1.8 cm is significant. While not all nodules that grow are cancerous, the fact that you have a history of rectal cancer raises the stakes. It is essential to consider that lung cancer can metastasize from other primary cancers, and your medical team is likely being cautious due to this risk.

The typical approach to managing lung nodules includes:
1. Monitoring: If the nodule is small and there are no other concerning features (like irregular borders or associated lymphadenopathy), doctors may recommend a follow-up CT scan in a few months to see if the nodule changes in size or appearance.

2. Further Imaging: Sometimes, a PET scan may be ordered to assess the metabolic activity of the nodule. Cancerous nodules often show increased uptake of the radioactive tracer used in PET scans.

3. Biopsy: If the nodule is concerning based on its characteristics or if it has grown, a biopsy may be recommended. This can be done via bronchoscopy, CT-guided needle biopsy, or surgical methods, depending on the nodule's location and the patient's overall health.

4. Surgical Resection: If there is a high suspicion of malignancy, surgical removal of the nodule may be the best option. This is often accompanied by a pathological examination of the tissue to determine if cancer is present.

Given your situation, it is understandable that you feel apprehensive about the urgency expressed by your healthcare providers. However, it is crucial to prioritize your health and follow their recommendations. If you are uncomfortable with the proposed plan, consider seeking a second opinion from another specialist, preferably one with experience in thoracic oncology.
In summary, while the presence of a lung nodule, especially one that has increased in size, can be concerning, the best course of action often involves a combination of monitoring, imaging, and possibly biopsy or surgical intervention. It is essential to communicate openly with your healthcare team about your concerns and preferences, as they can help guide you through the decision-making process based on your specific circumstances.

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