Managing Depression: Medication Insights and Emergency Relief Options - Psychiatry

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Depression medication consultation


Hello, doctor.
I am currently receiving treatment for anxiety and depression.
The doctor prescribed me: one dose of Lurasidone in the morning and one dose of Clonazepam before bed, with Xanax as needed for anxiety or panic attacks.
I would like to ask about depression symptoms.
Besides the daily medications, if I suddenly feel an intense sense of sadness that is really difficult to bear, is there any medication I can take temporarily to alleviate the symptoms? If so, could you please tell me the names of those medications?
My second question is that today I took two doses of Lurasidone, and I felt calm all day, even feeling quite good, which I haven't experienced in a long time.
Is this feeling due to taking an extra dose, or is it just a psychological effect? I will ask my doctor during my follow-up appointment, but I often find it hard to express my thoughts in front of the doctor, so I wanted to ask you first.
Thank you.

Haiyu, 30~39 year old female. Ask Date: 2021/03/26

Dr. Wu Enliang reply Psychiatry


Hello, online friend: I would like to ask about symptoms of depression.
Besides the daily medication that needs to be taken, is there any medication that can be taken temporarily to alleviate symptoms when feelings of sadness suddenly become overwhelming? If so, could you please tell me the names of those medications? A: In case of an emergency, you can take an as-needed medication like Xanax to relieve anxiety.
The second question is, I took two tablets of Lurasidone today, and I felt calm all day, even feeling quite good, which I haven't experienced in a long time.
Is this because I took an extra tablet or is it a psychological effect? A: If you have been taking it for a while (more than two weeks), it is possible that the medication is starting to take effect.
Dr.
Wu Enliang

Reply Date: 2021/03/26

More Info


Managing depression, particularly when it involves medication, can be a complex and nuanced process. It’s essential to understand both the pharmacological options available and the psychological strategies that can help manage acute symptoms.
Firstly, regarding your current medication regimen, it appears you are taking Lurasidone (referred to as 慮舒妥) in the morning and Mirtazapine (煩多閃) at night, along with Alprazolam (贊安諾) as needed for anxiety or panic attacks. Lurasidone is an atypical antipsychotic often used to treat major depressive disorder, while Mirtazapine is an antidepressant that can help with sleep and appetite, which is beneficial for those experiencing depression.

When it comes to managing sudden and severe feelings of sadness or depressive symptoms, there are a few options to consider. While there are no specific "as-needed" medications for depression like there are for anxiety (such as Alprazolam), some strategies can help alleviate acute distress:
1. Short-acting Benzodiazepines: While Alprazolam is primarily used for anxiety, it can sometimes help with acute depressive symptoms due to its calming effects. However, it’s crucial to use these sparingly due to the risk of dependence.

2. Antidepressant Adjustments: If you find that your depressive symptoms are becoming overwhelming, it’s essential to communicate this to your doctor. They may consider adjusting your current medications or adding a different antidepressant that can provide more immediate relief.

3. Crisis Medications: Some doctors may prescribe medications like Ketamine or Esketamine for severe depression, which can provide rapid relief in some cases. However, these treatments are typically administered in a clinical setting.

4. Psychotherapy: Engaging in therapy, particularly cognitive-behavioral therapy (CBT), can provide you with tools to manage acute feelings of sadness. Techniques learned in therapy can help you cope with overwhelming emotions when they arise.

5. Lifestyle Modifications: Incorporating regular physical activity, maintaining a balanced diet, and ensuring adequate sleep can significantly impact your mood and overall mental health. Mindfulness practices, such as meditation or yoga, can also help ground you during difficult moments.

Regarding your experience of feeling unusually calm and happy after taking an extra dose of Lurasidone, it’s essential to approach this with caution. While it’s possible that the additional dose contributed to your improved mood, it’s also important to consider the psychological aspect—sometimes, the expectation of feeling better can lead to a placebo effect. However, taking more than the prescribed dose can lead to side effects and should be avoided unless directed by your physician.

It’s crucial to have an open dialogue with your healthcare provider about your experiences, including any changes in mood or side effects you may be experiencing. If you find it challenging to express your thoughts during appointments, consider writing down your feelings and questions beforehand. This can help ensure that you communicate your needs effectively.

In summary, managing depression involves a combination of medication, therapy, and lifestyle changes. While there are options for acute relief, it’s essential to work closely with your healthcare provider to find the best approach tailored to your specific needs. Always prioritize safety and communicate openly about your experiences with medication and mood changes.

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