The urine test shows bacteria, but the doctor says there is no infection?
Hello, doctor.
I have been diagnosed with interstitial cystitis for a year.
During this year, I have undergone two rounds of hyaluronic acid injections, and my condition has been manageable.
However, after a medication injection in the second half of the year, I started experiencing urinary frequency, and I am now applying for a third round.
I went to another hospital where Dr.
A conducted a urinalysis, and the results showed bacteria but no white blood cells, so he advised against antibiotics.
However, the next day, at the hospital where I applied for the hyaluronic acid treatment, a bacterial culture showed growth, and Dr.
B identified it as Corynebacterium.
Dr.
B recommended that I take antibiotics.
I would like to ask if the presence of bacteria in the culture, despite the low white blood cell count, indicates an infection? Should I take antibiotics? Can drinking more water help flush out the bacteria? Currently, I do not have urinary frequency, but I still experience bladder pain from interstitial cystitis.
After taking antibiotics last time, I developed a vaginal infection that took six months to resolve, and I am now apprehensive about this situation.
I would like to confirm this.
Thank you, doctor!
Xiao Hua, 50~59 year old female. Ask Date: 2021/03/26
Dr. Li Minghui reply Urology
Hello: 1) Is there an infection? It may be related to your urine sample collection.
Was it done aseptically? For females, if not careful, an inappropriate sample can be obtained.
Please refer to the following guidelines from National Taiwan University Hospital: https://www.ntuh.gov.tw/labmed/Fpage.action?muid=4707&fid=51323.3.2.
Female patients should use a sterilized tissue (or a clean tissue if sterilized ones are unavailable) to wipe the genital area from the urethral opening downwards, ensuring cleanliness at the sampling site and preventing pubic hair from contaminating the urine collection container.
The first portion of urine should be voided into the toilet or urinal, and the second portion should be collected in the specimen container, with any remaining urine voided into the toilet or urinal.
2) If there is a urinary tract infection, diagnosis should be based on symptoms and test results.
If there are no symptoms but the urinalysis shows abnormalities, it may indicate a poor sample.
If symptoms are present but the tests are normal, some physicians may be concerned that it is an early-stage infection that is difficult to detect, and they may prescribe antibiotics.
Regarding the vaginal infection that occurred four days after taking antibiotics, due to the female anatomical structure, both conditions can coexist.
Wishing you good health, I personally recommend re-testing your urine.
Reply Date: 2021/03/26
More Info
Understanding the presence of bacteria in urine without the accompanying signs of infection can be quite complex, especially in the context of interstitial cystitis (IC) and prior urinary tract infections (UTIs). Your situation is particularly nuanced due to your history of interstitial cystitis and the recent findings from your urine tests.
Firstly, the presence of bacteria in urine without white blood cells (WBCs) can indicate a few possibilities. In a typical urinary tract infection, one would expect to see both bacteria and WBCs, as the latter are a sign of the body's immune response to infection. However, the absence of WBCs in your case suggests that there may not be an active infection, or it could indicate that the sample was contaminated or not collected properly. This is especially relevant for women, as improper collection can lead to the presence of bacteria that are not indicative of a true infection.
The bacteria identified in your culture, specifically "仙人掌菌" (Cactobacter), is not commonly associated with urinary tract infections. This raises the question of whether this finding is clinically significant. In many cases, the presence of bacteria in urine cultures can be a result of contamination, particularly if the patient is asymptomatic. If you are not experiencing symptoms such as dysuria (painful urination), frequency, urgency, or fever, it may be reasonable to consider that this finding does not warrant antibiotic treatment.
Regarding your concern about whether to take antibiotics, it is essential to weigh the risks and benefits. Antibiotics can disrupt the natural flora of the vagina and urinary tract, potentially leading to secondary infections such as yeast infections or bacterial vaginosis, which you have experienced in the past. Given your history of post-antibiotic vaginal infections, it may be prudent to avoid unnecessary antibiotic use unless there are clear signs of infection.
Drinking plenty of water can indeed help flush out bacteria from the urinary tract, but it is not a substitute for medical treatment if an infection is confirmed. Hydration is beneficial for urinary health and can help dilute urine, potentially alleviating some symptoms of interstitial cystitis. However, if the bacteria are indeed pathogenic and causing an infection, increased fluid intake alone may not be sufficient to clear the infection.
In summary, the presence of bacteria in your urine without WBCs, especially in the absence of symptoms, does not necessarily indicate an infection that requires antibiotic treatment. It is advisable to consult with a urologist or a healthcare provider who can interpret your urine culture results in the context of your symptoms and medical history. They may recommend a follow-up urine test or further evaluation to ensure that your interstitial cystitis is managed effectively without unnecessary interventions that could lead to complications.
In conclusion, while the presence of bacteria in urine can be concerning, it is crucial to consider the overall clinical picture, including symptoms and the specific type of bacteria identified. A careful approach that prioritizes your past experiences with antibiotics and infections will help guide the best course of action for your urinary health.
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