Does African Mango Tea Affect Birth Control Pill Efficacy? - Pharmacology

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Oral contraceptives


Hello Doctor, I am currently taking the contraceptive pill Estelle and also consuming a weight loss product called "African Mango Tea," which primarily contains African mango seed extract and black tea extract.
I would like to know if these two could affect the effectiveness of the contraceptive pill, potentially leading to its metabolism being altered.
How long should I wait between taking them? Or which one should I take first for better results? Here are the ingredients of Estelle: CYPROTERONE ACETATE 2.0000000000 MG and ETHINYL ESTRADIOL (EQUIVALENT TO ETHINYLOESTRADIOL) 0.0350000000 MG.
Thank you for your guidance.

Niming, 20~29 year old female. Ask Date: 2021/04/02

Dr. Zheng Shuwen reply Pharmacology


Hello, regarding your question, the response is as follows: "African mango tea" may delay gastric emptying, which could affect the efficacy of medications (such as oral contraceptives).
It is recommended that you do not take them simultaneously.
Wishing you all the best.
For inquiries, please contact Taoyuan Rehabilitation Hospital at: 03-3698553.
Working hours: Monday to Tuesday: 08:30-21:30; Wednesday to Friday: 08:30; Saturday: 08:30-13:30.

Reply Date: 2021/04/02

More Info


When it comes to the interaction between African Mango Tea and birth control pills, such as the one you are taking (Estelle), it is essential to consider the ingredients and how they may affect the metabolism of the contraceptive medication.
African Mango Tea is primarily made from the extract of the seeds of the African mango (Irvingia gabonensis) and may contain other components like red tea extract. While there is limited research specifically addressing the interaction between African Mango Tea and hormonal contraceptives, some herbal supplements can potentially influence the metabolism of medications by affecting liver enzymes, particularly cytochrome P450 enzymes, which are responsible for metabolizing many drugs, including hormonal contraceptives.

The active ingredients in Estelle, Cyproterone Acetate and Ethinyl Estradiol, are metabolized in the liver. If African Mango Tea were to induce or inhibit these enzymes, it could theoretically alter the effectiveness of the birth control pill. However, there is currently no strong evidence to suggest that African Mango Tea significantly impacts the efficacy of hormonal contraceptives.
To minimize any potential risk, it is advisable to space out the consumption of African Mango Tea and the birth control pill. Taking them at different times of the day may help reduce any possible interaction. For instance, if you take your birth control pill in the morning, consider having the tea later in the day.
Additionally, it is crucial to maintain consistent use of your birth control method. If you are concerned about the efficacy of your contraceptive, consider using additional protection, such as condoms, especially if you are consuming herbal products regularly.

Regarding the timing of consumption, there is no specific guideline on how long to wait between taking African Mango Tea and your birth control pill. However, a general rule of thumb is to allow a few hours between the two to ensure that the absorption and metabolism of the contraceptive are not compromised.

It's also important to note that while some people may use herbal supplements for weight loss or metabolic support, the safety and efficacy of these products can vary widely. Always consult with a healthcare provider before starting any new supplement, especially if you are on medication. They can provide personalized advice based on your health history and current medications.

In conclusion, while there is no definitive evidence that African Mango Tea affects the efficacy of birth control pills, it is prudent to take precautions. Space out the consumption of the tea and the pill, maintain consistent use of your contraceptive method, and consult with your healthcare provider for tailored advice. This approach will help ensure that you are protected against unintended pregnancy while also pursuing your health and wellness goals.

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