Impact of Missed Birth Control Pills on Contraceptive Effectiveness - Obstetrics and Gynecology

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Taking pre-exposure prophylaxis (PrEP), I forgot to take it at one point and even took a different brand as a supplement?


Hello doctor, I am currently taking the oral contraceptive Loette.
I have forgotten to take it three times, and each time I took the missed dose more than 12 hours late (taking two pills that day).
Additionally, there was one instance where I took a missed dose but used a different medication, Wenbunin (also taking two pills that day).
Will this affect the contraceptive effectiveness? Thank you, doctor.

Miss Chen, 20~29 year old female. Ask Date: 2021/04/06

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, the effectiveness of contraception may decrease, so it's best not to forget to take it.
Wishing you good health.

Reply Date: 2021/04/06

More Info


When it comes to the effectiveness of birth control pills, missing doses can significantly impact their contraceptive reliability. In your case, you mentioned that you are taking the birth control pill "Loestrin" (洛依欣) and that you have missed doses on three occasions, taking them more than 12 hours late, and once you took two pills on the same day to make up for a missed dose.
The general guideline for combination oral contraceptives, which include Loestrin, is as follows:
1. Missed Pills: If you miss a pill and it is less than 12 hours late, you should take the missed pill as soon as you remember and continue taking the rest of the pills at your regular time. In this case, your contraceptive protection remains intact.

2. More than 12 Hours Late: If you miss a pill and it is more than 12 hours late, the effectiveness of the pill may be compromised. In this situation, you should take the missed pill as soon as you remember, and then continue with your regular schedule. However, you should also use a backup method of contraception (like condoms) for the next seven days to ensure protection against pregnancy.

3. Double Dosing: Taking two pills in one day to make up for a missed dose is generally acceptable, but it’s important to note that this should not become a regular practice. It can lead to increased side effects, such as nausea or breakthrough bleeding.

4. Interactions with Other Medications: You mentioned taking "温不妊" (which I assume refers to a fertility-related medication). It's crucial to check if this medication interacts with your birth control pill. Some medications can reduce the effectiveness of hormonal contraceptives, so always consult with your healthcare provider about potential interactions.

Given your situation, since you missed doses on three occasions and took them more than 12 hours late, there is a possibility that your contraceptive effectiveness has been compromised during those cycles. It is advisable to use a backup contraceptive method for at least seven days following the missed pills.
Additionally, if you have unprotected intercourse during the time when your pill effectiveness is uncertain, there is a risk of pregnancy. If you are concerned about the possibility of pregnancy, consider taking a home pregnancy test or consulting your healthcare provider for further evaluation.

In summary, missed pills can indeed affect the effectiveness of birth control, especially if they are taken more than 12 hours late. Always follow the guidelines for missed pills and consult with your healthcare provider for personalized advice, especially when combining medications. Regular communication with your doctor can help ensure that you maintain effective contraceptive protection while managing any other health conditions you may have.

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