Abnormal Discharge After Antibiotic Treatment in Women - Obstetrics and Gynecology

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Secretions issues


Previously, I experienced lower abdominal pain due to an E.
coli infection and was prescribed stronger antibiotics.
Coincidentally, this occurred during my menstrual period (from the 26th to the 1st), so I was undergoing treatment while menstruating.
I'm not sure if it's related to the medication, but my menstrual flow was heavier than usual.
After my period ended, I noticed brown discharge for two days, which then changed to yellow discharge (which has increased, requiring the use of panty liners).
I also experienced soreness on both sides of my lower abdomen (which had improved significantly after treatment but has suddenly returned).
Occasionally, there is a bit of bleeding.
Previously, my vaginal discharge was clear, colorless, and odorless, and during ovulation, it would only become egg white-like in consistency.
However, this time, with the color change and lower abdominal pain, I visited a large hospital.
The doctor performed a pelvic exam and ultrasound, stating that everything appeared normal and that I would likely pass it (there were just some red follicles internally, which may disappear by the next menstrual cycle).
They diagnosed it as ovulation bleeding.
Now, four days later, the discharge has decreased, and the pain is less severe, but the color remains yellow and has not changed at all.
It feels like this will last a long time.
Should I use a suppository or undergo further testing? Is it still safe to engage in sexual activity?

Yo, 20~29 year old female. Ask Date: 2021/04/07

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it may be inflammation.
I recommend visiting a gynecologist for an examination.
Wishing you good health.

Reply Date: 2021/04/07

More Info


Abnormal vaginal discharge after antibiotic treatment can be a common concern for many women, especially following a course of strong antibiotics for infections like E. coli. Antibiotics can disrupt the natural balance of bacteria in the vagina, leading to changes in discharge, potential overgrowth of yeast, or other infections.
In your case, it seems that the antibiotic treatment coincided with your menstrual cycle, which can also affect the characteristics of your discharge. It's not unusual for women to experience changes in their menstrual flow or discharge during or after antibiotic treatment. The increase in discharge, particularly if it has changed to a yellow color, could indicate several possibilities:
1. Residual Effects of Antibiotics: Antibiotics can alter the normal vaginal flora, leading to an imbalance that may result in increased discharge. This discharge can sometimes appear yellow, especially if there is a mild infection or irritation.

2. Yeast Infection: Antibiotics can lead to an overgrowth of yeast (Candida), which may cause a thick, yellowish discharge, often accompanied by itching or irritation. If you notice any additional symptoms such as itching, burning, or a cottage cheese-like consistency, it may be indicative of a yeast infection.

3. Bacterial Vaginosis (BV): This condition can also arise after antibiotic use, characterized by a fishy odor and a change in discharge. Although BV is usually associated with a grayish discharge, it can sometimes present with yellowish discharge as well.

4. Hormonal Changes: The hormonal fluctuations during your menstrual cycle can also contribute to changes in discharge. The presence of red follicles noted during your ultrasound could be related to ovulation or hormonal changes, which might explain the discomfort and discharge changes.

Given that your doctor has performed an internal examination and ultrasound, and found everything to be normal, it is a positive sign. However, if the yellow discharge persists, or if you experience increased discomfort, it would be wise to follow up with your healthcare provider. They may recommend further testing, such as a vaginal swab, to rule out infections like BV or a yeast infection.

Regarding the use of vaginal suppositories, it is essential to consult your healthcare provider before starting any new treatment. Self-treating with over-the-counter products without a proper diagnosis may lead to further complications or disrupt the natural flora even more.

As for sexual activity, if you are not experiencing significant discomfort and your doctor has not advised against it, it may be safe to engage in sexual intercourse. However, if you have concerns about discharge or discomfort during sex, it is best to wait until you have consulted with your healthcare provider.

In summary, while changes in discharge after antibiotic treatment can be concerning, they are often manageable. Monitoring your symptoms, maintaining open communication with your healthcare provider, and seeking further evaluation if necessary will help ensure your health and well-being.

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