Breast Cancer Risk: Genetics vs. Lifestyle Factors

What is the likelihood of inheritance?

Hello Doctor, my father is 82 years old.
Last August, he discovered a lump near his chest close to the armpit, but he did not pay much attention to it at the time.
It wasn't until early January this year that he went for a biopsy, which revealed breast cancer.
The doctor did not specify the stage and mentioned that my father does not need any treatment because he had previously fainted due to carbon dioxide buildup in his body last August, but he was revived.
However, my father's lung function is poor, and he requires an oxygen machine at home.
I am unsure if his age and health condition make him unsuitable for any surgery or radiation therapy.
Currently, the doctor said medication could control the cancer for a few years, and he is under observation.
The doctor also mentioned that at my father's age, hereditary factors are unlikely to be significant, and it is more likely influenced by diet and emotions.
My father is abroad, and my mother informed me of the situation, which has raised my concerns as I have a 2.5-year-old child and I fear my risk of developing breast cancer may increase.
I have been monitoring breast cyst changes (fluid-filled sacs) annually for several years.

Now, I would like to ask the doctor: does my father's diagnosis of breast cancer at this age increase my risk of developing breast cancer? Can the medication help my father live a few more years? What do you think about the hereditary risk? Is an annual breast ultrasound sufficient for me? Thank you for your response, Doctor.

Miss Lin, 40~49 year old female. Ask Date: 2021/04/12

Dr. Yuan Tianmin reply Breast and Thyroid

Your father is elderly and has pre-existing lung issues, so the doctor may not recommend a more standard treatment approach.
However, I personally suggest that the tumor should at least be removed, as it could potentially bleed and lead to ulceration of the wound, making care more complicated.
As for your father's breast cancer, there is certainly a possibility that it could be hereditary.
Currently, a breast ultrasound should be sufficient.

Reply Date: 2021/04/12

More Info

Breast cancer is a complex disease influenced by a combination of genetic and lifestyle factors. Understanding the interplay between these factors is crucial for assessing individual risk and making informed health decisions.

Firstly, the BRCA1 and BRCA2 genes are well-known for their association with hereditary breast and ovarian cancer. Individuals who inherit mutations in these genes have a significantly increased risk of developing breast cancer, with estimates suggesting that women with a BRCA1 mutation have a 55-65% chance of developing breast cancer by age 70, while those with a BRCA2 mutation have a 45% chance. However, it is essential to note that not having mutations in these genes does not eliminate the risk of breast cancer; it merely reduces the likelihood. Other genetic factors, environmental influences, and lifestyle choices also play significant roles in breast cancer risk.

In your father's case, the diagnosis of breast cancer at an advanced age (82 years) is relatively uncommon, as breast cancer is more frequently diagnosed in women. The fact that your father has other health issues, such as compromised lung function, complicates treatment options. In older adults, especially those with significant comorbidities, the risks associated with surgery or aggressive treatments like chemotherapy may outweigh the potential benefits. Therefore, a palliative approach focusing on medication to manage symptoms and improve quality of life is often recommended.

Regarding your concerns about hereditary risk, while your father's diagnosis may raise questions about genetic predisposition, breast cancer in men is rare and typically does not have the same hereditary implications as it does in women. The likelihood of you inheriting a significant genetic risk from your father is low, especially if there is no known family history of breast cancer in women. However, it is essential to consider that breast cancer can occur sporadically due to a variety of factors, including lifestyle and environmental influences.

As for your own health, regular monitoring is crucial. Annual breast ultrasounds are a good practice, especially if you have a history of breast cysts. However, discussing your concerns with a healthcare provider who can evaluate your personal and family medical history is vital. They may recommend genetic counseling or testing if there are indications of a hereditary cancer syndrome in your family.

Lifestyle factors, such as diet, exercise, and stress management, can also influence cancer risk. While improving these factors may not eliminate the risk of breast cancer, they can contribute to overall health and potentially lower the risk of various diseases, including cancer. A balanced diet rich in fruits, vegetables, whole grains, and lean proteins, along with regular physical activity, can help maintain a healthy weight and reduce the risk of chronic diseases.

In summary, while your father's breast cancer diagnosis may raise concerns about your risk, the hereditary implications are likely minimal, especially given his age and the rarity of male breast cancer. Regular monitoring and a healthy lifestyle are essential components of your health strategy. If you have further concerns, consider consulting with a genetic counselor or a healthcare professional specializing in breast health for personalized advice and guidance.

Similar Q&A

Can Lifestyle Changes Reduce Cancer Risk in Genetic Cases?

Hello: I would like to ask, many people say that changing lifestyle habits can reduce the risk of cancer, but for hereditary cancers (such as breast cancer and colorectal cancer), can improving lifestyle or dietary habits effectively lower the risk of developing these cancers?

Dr. Zeng Yuhua reply Oncology
Hello! Good dietary habits can somewhat reduce the risk of cancer. As you mentioned, both breast cancer and colorectal cancer are somewhat related to a high-fat diet, and of course, a family history should be taken into special consideration. The causes of cancer are often relate...

Understanding Breast Cancer Risk and Evening Primrose Oil: What You Need to Know

Hello, my mother had a liver tumor (which has been surgically removed) and later was diagnosed with breast cancer (which was not metastatic and has also been surgically removed). Does this indicate a potential hereditary risk for breast cancer? I read online that individuals with...

Dr. Cai Yonglong reply Obstetrics and Gynecology
Dear Mia, The term hereditary breast cancer is currently understood in the medical field as being associated with the presence of BRCA1 or BRCA2 genes. However, these genes are generally not used as screening tools since they account for a relatively small proportion of breast c...

Understanding BRCA1 and BRCA2: Do Normal Genes Prevent Breast Cancer?

Having normal BRCA1 and BRCA2 genes does not guarantee that an individual will not develop breast cancer. While mutations in these genes are associated with a higher risk of breast and ovarian cancers, the presence of normal genes does not eliminate the possibility of developing ...

Dr. Wu Xianghui reply Obstetrics and Gynecology
No, it's just a lower probability.

Understanding the Link Between Birth Control Pills and Breast Cancer Risk

Hello Dr. Lai: I would like to ask you a few questions: Is it advisable for individuals with a family history of breast cancer to use oral contraceptives? Does the dosage of contraceptives have an impact on breast cancer? If one wants to prevent excessive estrogen effects on the ...

Dr. Lai Yicheng reply Oncology
Hello: Currently, epidemiological studies have not confirmed a link between the use of oral contraceptives and the risk of breast cancer. The relationship between breast cancer and genetic inheritance, as well as dietary habits, is much clearer. If you have a family history that ...