Acanthamoeba Infection Risks and Treatments for Eye Health - Ophthalmology

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The issue of Abami infection?


1.
I would like to ask if individuals with low immunity (such as leukemia patients) have a higher risk of eye infections from Acanthamoeba, especially if water splashes into their eyes.

2.
If infected, would using [Systane] eye drops for treating red eyes be effective?
3.
If that is not effective, what medication should be used?
4.
I visited a clinic where they promoted taking lutein.
What are the functions of lutein?

Niming, 10~19 year old female. Ask Date: 2021/04/19

Dr. Gao Pilin reply Ophthalmology


Hello: 1.
Generally speaking, if the cornea is not damaged, it is not easily susceptible to infection.
2.
It is ineffective.
3.
You need to use medication specifically for amoebic infections, which is usually not available for purchase.
Typically, you should consult an ophthalmologist at a major hospital.
4.
Lutein is primarily for the maintenance of the retina.
Please refer to: https://bit.ly/2P2STKT Taiwan E-Hospital Puzi Hospital Ophthalmology: Monday, Tuesday, Thursday, and Friday mornings from 8:00 AM to 12:00 PM; Wednesday afternoons from 2:00 PM to 4:30 PM.
Online responses can only serve as a reference; if necessary, you should seek medical attention at a healthcare facility.
I hope to have the opportunity to serve you.
Gao Pilin

Reply Date: 2021/04/19

More Info


Acanthamoeba infection is a serious concern, particularly for individuals with compromised immune systems, such as those suffering from leukemia. The Acanthamoeba species are free-living amoebae that can cause severe infections in the eye, known as Acanthamoeba keratitis. This condition is often associated with contact lens wearers, but it can also occur in individuals who have had exposure to contaminated water, such as swimming pools, hot tubs, or even tap water.

1. Risk of Infection in Immunocompromised Individuals: For individuals with weakened immune systems, such as leukemia patients, the risk of Acanthamoeba infection is indeed higher. Their compromised immune response makes it more difficult for their bodies to fight off infections, including those caused by Acanthamoeba. If water containing the amoeba comes into contact with the eyes, the likelihood of developing an infection increases significantly. Therefore, it is crucial for immunocompromised individuals to take extra precautions to avoid exposure to potentially contaminated water.

2. Effectiveness of "沙龍" (Saline Solution): If an individual is infected with Acanthamoeba, using a standard eye drop solution like "沙龍" (which is likely a saline solution) is not effective. Acanthamoeba keratitis requires specific treatment, typically involving the use of topical anti-amoebic medications such as chlorhexidine or propamidine isethionate. These medications are specifically designed to target and eliminate the Acanthamoeba organisms. Therefore, relying on a saline solution will not resolve the infection and could lead to further complications.

3. Recommended Treatments: If an Acanthamoeba infection is suspected or confirmed, it is essential to seek immediate medical attention from an ophthalmologist. The treatment regimen usually involves a combination of anti-amoebic medications, and in some cases, corticosteroids may be prescribed to reduce inflammation. It is important to follow the treatment plan as prescribed by a healthcare professional, as untreated Acanthamoeba keratitis can lead to severe complications, including vision loss.

4. Lutein and Its Benefits: Regarding lutein, it is a carotenoid that is often marketed for its potential benefits in eye health. Lutein is known for its role in protecting the retina from oxidative stress and may help reduce the risk of age-related macular degeneration (AMD) and cataracts. It is believed to filter harmful blue light and contribute to overall visual health. While lutein can be beneficial, it is important to note that it is not a treatment for infections like Acanthamoeba keratitis. Instead, it is more of a preventive measure for maintaining eye health over the long term.

In summary, individuals with compromised immune systems, such as leukemia patients, are at a higher risk for Acanthamoeba infections. Standard saline solutions are not effective treatments for such infections, and specific anti-amoebic medications are required. It is crucial for anyone suspecting an Acanthamoeba infection to consult an ophthalmologist promptly. While lutein can support eye health, it should not be considered a treatment for infections. Regular eye check-ups and maintaining good hygiene practices, especially for contact lens wearers, are essential for preventing infections.

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