Emergency Contraceptives and Their Impact on Uterine Fibroids - Obstetrics and Gynecology

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Emergency contraceptive pills and uterine fibroids?


Last month, I was taking the emergency contraceptive pill, but I missed a dose during the last week, which led to abnormal bleeding.
I consulted a doctor who suggested it might be due to injury and prescribed hemostatic medication.
However, I only took it for one day because my menstrual cycle was about to start, and I was concerned it might affect my period, so I stopped taking it.
During this time, I experienced light bleeding.
After my normal menstrual flow lasted for 7 days, I did not continue taking the emergency contraceptive pill, and my next period was delayed by a week.
I saw a doctor who prescribed medication to regulate my cycle, and my period started.
However, during an ultrasound, the doctor mentioned that I might be developing uterine fibroids, which could be caused by the contraceptive pill.
Yet, I have read in other literature that contraceptive pills can help prevent gynecological diseases, including uterine fibroids.
I would like to understand whether the contraceptive pill will have an impact on this.

Lin, 10~19 year old female. Ask Date: 2021/04/20

Dr. Huang Yuande reply Obstetrics and Gynecology


In principle, short-term use will not cause changes in uterine fibroids, so taking it for just a few days should not have an impact.
However, since taking oral contraceptives can disrupt the menstrual cycle, there may be some light bleeding.

Reply Date: 2021/04/20

More Info


Emergency contraceptives (ECs) and their relationship with uterine fibroids is a complex topic that involves understanding both the pharmacological effects of these medications and the pathophysiology of uterine fibroids.
First, let's clarify what emergency contraceptives are. ECs, such as Levonorgestrel and Ulipristal acetate, are designed to prevent pregnancy after unprotected intercourse or contraceptive failure. They work primarily by delaying ovulation, inhibiting fertilization, or preventing implantation of a fertilized egg.
Regarding your concern about the potential impact of emergency contraceptives on uterine fibroids, it is important to note that the evidence surrounding this issue is not entirely conclusive. Uterine fibroids, also known as leiomyomas, are benign tumors of the uterus that can cause a variety of symptoms, including heavy menstrual bleeding, pelvic pain, and reproductive issues. The development of fibroids is influenced by several factors, including hormonal levels, particularly estrogen and progesterone.

The relationship between hormonal contraceptives, including ECs, and fibroid development is multifaceted. Some studies suggest that hormonal contraceptives may have a protective effect against the development of fibroids, while others indicate that they could potentially exacerbate existing fibroids or contribute to their growth. For instance, the estrogen component in many contraceptives can stimulate the growth of fibroids, as these tumors are often sensitive to estrogen. However, the progestin component may counteract this effect to some extent.

In your case, it seems that you experienced irregular bleeding and other symptoms after missing doses of your regular contraceptive pill (玫麗安). This irregularity could be due to hormonal fluctuations caused by inconsistent pill intake rather than the use of emergency contraception. Additionally, the fact that your doctor mentioned the possibility of developing fibroids suggests that they are monitoring your reproductive health closely.
It is also worth noting that while some literature suggests that hormonal contraceptives can help manage symptoms associated with fibroids, such as heavy menstrual bleeding, they do not necessarily prevent the formation of new fibroids. In fact, some women may find that their fibroid symptoms improve with hormonal treatment, while others may not experience the same benefits.

In conclusion, while emergency contraceptives may have some influence on hormonal levels, their direct impact on the formation or growth of uterine fibroids is not well established. If you have concerns about fibroids or the effects of hormonal contraceptives on your reproductive health, it is essential to have an open dialogue with your healthcare provider. They can offer personalized advice based on your medical history, current symptoms, and any imaging studies that have been performed. Regular monitoring and appropriate management can help address any issues related to fibroids and ensure that your reproductive health remains a priority.

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