Lymph Node Swelling and Its Connection to Sinusitis - Otolaryngology

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Cervical lymphadenitis


Hello, doctor...
I have undergone a bacterial culture that identified Staphylococcus as the cause of my sinusitis, and I am currently being treated with Moxifloxacin.
On Monday, I noticed swelling near my parotid gland, which is painful when pressed.
Additionally, there is a soft lymph node about 0.5 cm below that is also painful upon pressure.
I quickly returned to the clinic at Linkou Chang Gung Memorial Hospital, where the doctor confirmed that there is only one enlarged lymph node.
The doctor then performed an endoscopy to check for any issues in the nasopharynx, which appeared normal, although the symptoms of sinusitis persist.
The doctor mentioned that the lymph node issue is due to an infection and prescribed Amoxicillin, advising me to return for a follow-up in a week.
My question is, will this lymph node enlargement resolve? Is it related to the sinusitis? Thank you for your assistance.

Niming, 40~49 year old female. Ask Date: 2021/04/22

Dr. Zheng Jueyi reply Otolaryngology


Hello: Common lymphadenopathy with pain is often related to infections, which may be associated with sinusitis or parotitis.
In most cases, lymphadenopathy will decrease or resolve after the infection improves.
It is recommended to complete the course of medication before returning for evaluation.
Wishing you peace and health.
Sincerely, Dr.
Jue-Yi Cheng, Director of the Department of Otolaryngology, Taoyuan General Hospital, Ministry of Health and Welfare.

Reply Date: 2021/04/22

More Info


Lymph node swelling, particularly in the context of sinusitis, is a common clinical scenario that can cause concern for many patients. In your case, it appears that you have been diagnosed with a bacterial sinus infection caused by Staphylococcus aureus, and you are currently undergoing treatment with antibiotics. The swelling and tenderness in the lymph nodes, especially near the parotid gland (the major salivary gland located near the jaw), can indeed be related to your sinus infection.

When the body is fighting an infection, the immune system responds by activating lymph nodes, which are part of the lymphatic system. These nodes act as filters for harmful substances and are crucial in the immune response. Infections, whether they are bacterial, viral, or fungal, can lead to lymphadenopathy, which is the medical term for swollen lymph nodes. In your case, the lymph node you described as soft and painful is likely reacting to the infection in your sinuses.

The connection between sinusitis and lymph node swelling can be explained through the pathway of infection. The sinuses are closely located to various lymphatic drainage areas, and when the sinuses become inflamed or infected, the lymphatic system may respond by swelling the nearby lymph nodes. This is a normal physiological response, indicating that your body is working to fight off the infection.
As for your specific question about whether the lymph node swelling will resolve, the answer is generally yes. Once the underlying infection is treated effectively with antibiotics, the lymph nodes should gradually return to their normal size. It is important to complete the full course of antibiotics as prescribed by your physician, even if you start to feel better before finishing the medication. This ensures that the infection is fully eradicated and reduces the risk of developing antibiotic resistance.

In terms of follow-up, it is advisable to monitor the lymph node size and tenderness. If the swelling persists beyond a few weeks after completing your antibiotic treatment, or if you experience any new symptoms such as fever, night sweats, or unexplained weight loss, you should return to your healthcare provider for further evaluation. They may consider additional diagnostic tests, such as imaging studies or further blood tests, to rule out other potential causes of lymphadenopathy.

In summary, the swelling of your lymph node is likely a response to your ongoing sinus infection. With appropriate antibiotic treatment, it is expected that the lymph node will decrease in size and tenderness. Always keep an open line of communication with your healthcare provider regarding any concerns or changes in your symptoms, as they can provide the best guidance tailored to your specific situation.

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