Proteinuria: Should You Worry About Kidney Health? - Urology

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Urinary protein


Hello doctor, I went for a health check and found that I have protein in my urine (++).
Does this mean I have kidney problems? However, a month before the health check, I had an ultrasound of my kidneys, and the doctor said there were no issues.
Do I need to go to a larger hospital for further examination? Also, what tests should I undergo?

Xiao Pang, 20~29 year old female. Ask Date: 2021/04/27

Dr. Du Shixi reply Urology


Hello: The presence of protein in the urine is a phenomenon that requires attention to lifestyle factors (such as diet, rest, and blood pressure).
Generally, an ultrasound examination is sufficient.
I personally recommend that if a family member has a history of kidney disease or if you have symptoms, you should get checked at a major hospital.
If not, it is advisable to have several tests over time to see if there is any improvement, while paying attention to lifestyle and dietary habits.
Wishing you good health.

Reply Date: 2021/04/27

More Info


Proteinuria, or the presence of excess protein in the urine, can be an important indicator of kidney health. When you find out that you have proteinuria, it is understandable to be concerned about your kidney function. However, the interpretation of proteinuria and its implications for kidney health can vary based on several factors, including the amount of protein detected, the presence of other symptoms, and your overall health history.

Firstly, it is essential to understand that proteinuria can be classified into different categories based on the amount of protein present in the urine. A mild level of proteinuria (less than 150 mg/day) may not indicate significant kidney damage, while moderate to severe proteinuria (greater than 500 mg/day) can be a sign of kidney disease or damage. In your case, the presence of protein in your urine (indicated as "++") suggests that further evaluation may be warranted, especially if this finding is new or has changed from previous tests.

You mentioned that you had a kidney ultrasound a month ago, and the doctor indicated that your kidneys appeared normal. This is a positive sign, as it suggests that there may not be any structural abnormalities in the kidneys at that time. However, it is important to note that kidney function can change over time, and the presence of proteinuria can sometimes indicate early kidney disease, even if imaging studies appear normal.

Given your situation, it would be prudent to follow up with a healthcare provider, particularly a nephrologist (a kidney specialist), for further evaluation. They may recommend additional tests to assess your kidney function more comprehensively. Common tests include:
1. Urine Protein-to-Creatinine Ratio (PCR): This test compares the amount of protein to creatinine in a single urine sample, providing an estimate of daily protein excretion.

2. 24-Hour Urine Collection: This test measures the total protein excretion over a full day, which can help determine the severity of proteinuria.

3. Blood Tests: These may include serum creatinine and blood urea nitrogen (BUN) tests to assess kidney function and glomerular filtration rate (GFR).

4. Additional Imaging: If there are concerns about kidney structure or function, further imaging studies may be warranted.

5. Blood Pressure Monitoring: Since hypertension can contribute to kidney damage, monitoring your blood pressure is essential.

In terms of lifestyle modifications, it is advisable to maintain a balanced diet, manage your blood pressure, and stay hydrated. If you have risk factors for kidney disease, such as diabetes or hypertension, controlling these conditions is crucial for kidney health.

In conclusion, while the presence of proteinuria can be concerning, it does not automatically mean you have significant kidney disease, especially if previous imaging studies were normal. However, it is essential to follow up with a healthcare provider for a thorough evaluation and to determine the appropriate next steps. Early detection and management of any potential kidney issues can significantly impact long-term kidney health.

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