How to Treat Persistent Mosquito Bite Blisters on Your Skin - Dermatology

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Mosquito bites can cause blisters?


Hello, doctor.
A week ago, I was bitten by a mosquito on my ankle, and the next day it swelled up, causing redness and swelling that extended to my calf, along with a blister that is about 2 centimeters in diameter.
After a few days, it hasn't gone down.
Two days ago, I visited a doctor who punctured the blister and bandaged it, but it seems that the small hole the doctor made is healing while the blister has not decreased at all.
What further treatment can I pursue?

Flora, 20~29 year old female. Ask Date: 2021/05/02

Dr. Wu Yuxin reply Dermatology


You should consult your primary care physician about this issue, as they are most familiar with your medical condition.

Reply Date: 2021/05/02

More Info


When dealing with persistent mosquito bite blisters, it's important to understand the body's reaction to insect bites and the appropriate treatment options available. Mosquito bites can lead to localized swelling, redness, and the formation of blisters, especially in individuals who may have a heightened sensitivity or allergic reaction to the insect's saliva.
In your case, it seems that the blister on your ankle has not resolved even after medical intervention. Here are some steps and considerations for managing this condition:
1. Avoid Scratching: It's crucial to resist the urge to scratch the blister or the surrounding area. Scratching can lead to secondary infections, which can complicate the healing process and prolong recovery.

2. Keep the Area Clean: Maintain cleanliness around the blister. Gently wash the area with mild soap and water to prevent infection. After cleaning, pat the area dry with a clean towel.

3. Use a Protective Dressing: If the blister is still intact, consider covering it with a sterile bandage to protect it from further irritation and to keep it clean. If the blister has been drained, apply a sterile dressing to protect the open skin.

4. Topical Treatments: Over-the-counter hydrocortisone cream can help reduce inflammation and itching. Additionally, applying an antibiotic ointment (like Neosporin) can help prevent infection if the blister has been punctured.

5. Cold Compress: Applying a cold compress to the area can help reduce swelling and provide relief from itching. Make sure to wrap ice in a cloth to avoid direct contact with the skin.

6. Oral Antihistamines: If you are experiencing significant itching or discomfort, consider taking an oral antihistamine, such as diphenhydramine (Benadryl), which can help alleviate allergic reactions and reduce itching.

7. Monitor for Signs of Infection: Keep an eye on the blister for any signs of infection, such as increased redness, warmth, swelling, pus, or fever. If you notice any of these symptoms, it is important to seek medical attention promptly.

8. Consult a Dermatologist: Since the blister has not improved after initial treatment, it may be beneficial to follow up with a dermatologist. They can assess the situation more thoroughly and may recommend additional treatments, such as prescription topical steroids or other medications.

9. Prevent Future Bites: To prevent future mosquito bites, consider using insect repellent containing DEET, wearing long sleeves and pants when outdoors, and using screens or nets in living areas.

10. Allergy Consideration: Given your history of asthma and potential allergic reactions, it may be worthwhile to discuss with your healthcare provider whether you should be evaluated for allergies to mosquito bites or other environmental factors.

In summary, while mosquito bites can be bothersome and lead to complications like blisters, proper care and monitoring can help manage the symptoms effectively. If the situation does not improve, or if you have concerns about the healing process, do not hesitate to seek further medical advice.

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