the Link Between GERD and Helicobacter Pylori Infection - Gastroenterology and Hepatology

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Gastroesophageal reflux disease (GERD) and Helicobacter pylori?


I have gastroesophageal reflux disease (GERD) and underwent an endoscopy.
The doctor confirmed the presence of reflux and asked if I wanted to undergo eradication therapy for Helicobacter pylori.
I would like to understand the relationship between Helicobacter pylori and reflux.
After eradication therapy, is it possible that my reflux will improve? I have seen articles suggesting that it might actually worsen the reflux.
Thank you.

Lucas, 20~29 year old female. Ask Date: 2021/05/07

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: It is recommended to eradicate Helicobacter pylori if there is a gastric ulcer.
However, if there is no gastric ulcer, eradication is not necessarily required, except in cases of anemia or a family history of gastric cancer.
In my opinion, when treating gastroesophageal reflux disease (GERD), there is no need to consider the issue of Helicobacter pylori.
Allowing Helicobacter pylori to damage the gastric mucosa (the cells that secrete gastric acid) to reduce gastric acid is unnecessary.
Treatment for GERD should focus on lifestyle and dietary habits, avoiding tea (black tea/green tea/milk tea), coffee, spicy foods, fried foods, high-fat, and high-protein foods, which is the best approach.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2021/05/07

More Info


Gastroesophageal reflux disease (GERD) and Helicobacter pylori (H. pylori) infection are two conditions that can significantly impact gastrointestinal health. Understanding the relationship between them is essential for effective management and treatment.

H. pylori is a type of bacteria that infects the stomach lining and is known to cause various gastrointestinal disorders, including gastritis and peptic ulcers. The presence of H. pylori can lead to inflammation of the stomach lining, which may contribute to symptoms such as abdominal pain, bloating, and nausea. In some cases, it can also exacerbate GERD symptoms.

GERD occurs when stomach acid frequently flows back into the esophagus, leading to irritation and inflammation. This condition can be influenced by several factors, including diet, lifestyle, and anatomical issues such as a hiatal hernia. The relationship between H. pylori and GERD is complex and somewhat controversial. Some studies suggest that H. pylori infection may actually have a protective effect against GERD, while others indicate that eradicating the bacteria can improve GERD symptoms.

When it comes to the treatment of H. pylori, the standard approach involves a combination of antibiotics and proton pump inhibitors (PPIs). PPIs reduce stomach acid production, which can help heal the stomach lining and alleviate symptoms associated with H. pylori infection. However, there is a concern that reducing stomach acid may lead to an increase in GERD symptoms in some patients. This is because stomach acid plays a role in the digestive process, and when its production is inhibited, it can lead to changes in gastric motility and increased pressure in the stomach, potentially worsening reflux symptoms.

In your case, if you have been diagnosed with both GERD and H. pylori infection, it is crucial to discuss your treatment options with your healthcare provider. They can help determine whether the benefits of eradicating H. pylori outweigh the potential risks of worsening GERD symptoms. In some instances, treating H. pylori may lead to an improvement in GERD symptoms, particularly if the infection is causing significant inflammation or contributing to other gastrointestinal issues.

Moreover, lifestyle modifications can also play a significant role in managing GERD. These may include dietary changes, weight management, avoiding triggers such as spicy foods and caffeine, and elevating the head of the bed to reduce nighttime reflux. It is essential to adopt a comprehensive approach that addresses both the infection and the reflux symptoms.

In summary, while there is a relationship between H. pylori infection and GERD, the effects of treating H. pylori on GERD symptoms can vary from person to person. It is essential to work closely with your healthcare provider to develop a tailored treatment plan that considers your specific symptoms and health history. By addressing both conditions, you can achieve better overall gastrointestinal health and improve your quality of life.

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