How long does it take for gastroesophageal reflux disease (GERD) to improve when taking proton pump inhibitors (PPIs)? What should I do if I experience a bitter taste and acid reflux after stopping PPIs?
Hello: In February of this year, I underwent an upper gastrointestinal endoscopy, which diagnosed me with gastroesophageal reflux disease (GERD) and esophagitis.
Initially, the doctor only mentioned GERD and did not provide further details.
I was prescribed esomeprazole (a proton pump inhibitor, PPI) and hyoscine butylbromide (an antispasmodic) to take daily.
After three months, in the fourth month, the doctor prescribed the same medications again.
I sometimes experience pain in the upper left abdomen, which occasionally resolves on its own.
I also have skin urticaria at times and a sensation of swelling in my throat.
I consulted a different doctor, who reviewed my medical history and classified my condition as Grade C.
He diagnosed my upper left abdominal pain as irritable bowel syndrome (IBS) and advised that I only take the antispasmodic when in pain, rather than daily, as it can cause constipation.
Due to the urticaria, he switched my esomeprazole (Grade C medication) to famotidine (Grade B medication), to be taken once in the morning and once at night.
However, when I stopped taking esomeprazole, I experienced a bitter taste and acid reflux that day, indicating mild gastroesophageal reflux, along with a bitter taste in my mouth.
I am very concerned about potential damage to my esophagus.
I had to resume taking esomeprazole, but I still feel a sensation of swelling in my throat.
Since taking the PPI, I often feel somewhat unwell and worry that my esophagitis is not improving.
Is Grade C GERD with esophagitis considered serious? Will it improve? Is it curable? How long should I take the PPI before I can stop? What should I do if I experience a bitter taste and acid reflux after stopping the PPI? Thank you for your response, and I appreciate it!
Cynthia, 40~49 year old female. Ask Date: 2021/05/10
Dr. Cai Anshun reply Gastroenterology and Hepatology
Hello: Gastroesophageal reflux disease (GERD) is classified into four grades (A, B, C, D) based on the extent of esophageal mucosal injury due to gastric acid, according to the Los Angeles Classification.
Under the National Health Insurance regulations, grades A and B allow for proton pump inhibitor therapy for a maximum of four months; grades C and D allow for a maximum of twelve months.
Some patients with milder symptoms may not experience any symptoms during the treatment period and may not need to continue medication until the end of the prescribed duration.
The key is to carefully identify lifestyle and dietary habits that may exacerbate gastroesophageal reflux and make necessary improvements to achieve a cure.
(Factors such as tea (black tea/green tea/milk tea), coffee, chocolate, sweets, spicy foods, fried foods, high-fat and high-protein foods, being underweight or overweight, and constipation may all be potential contributors.) Changhua Hospital cares about your health.
Dr.
Tsai An-shun.
Reply Date: 2021/05/10
More Info
Managing gastroesophageal reflux disease (GERD) and esophagitis can be a complex process, especially when it involves the use of proton pump inhibitors (PPIs) and the presence of additional symptoms such as abdominal pain, skin reactions, and throat discomfort. Your situation, as described, raises several important points regarding the duration of PPI use, potential side effects, and the management of your symptoms.
Firstly, it's essential to understand that GERD is a chronic condition characterized by the backflow of stomach contents into the esophagus, leading to symptoms such as heartburn, regurgitation, and discomfort. Esophagitis, which is inflammation of the esophagus, can occur as a result of this reflux. The treatment typically involves lifestyle modifications, dietary changes, and medications such as PPIs, which work by reducing stomach acid production.
Regarding your concern about the severity of your condition, a classification of "C-level" indicates a moderate level of severity in terms of esophagitis. While it may sound concerning, many patients with C-level esophagitis can achieve significant improvement with appropriate treatment. The key is to adhere to your prescribed medication regimen and follow up with your healthcare provider regularly.
You mentioned experiencing symptoms such as a bitter taste in your mouth and throat discomfort upon discontinuing the PPI. This is not uncommon, as stopping PPIs can lead to a rebound effect where acid production temporarily increases, resulting in symptoms of reflux. If you find that you cannot tolerate stopping the PPI without experiencing significant discomfort, it may be necessary to continue the medication for a longer duration, under the guidance of your physician.
The duration of PPI therapy can vary widely among individuals. Some patients may require long-term therapy, while others may be able to taper off after a few months. The decision to stop or continue PPI therapy should be based on your symptom control, the severity of your esophagitis, and any potential side effects you may be experiencing. Regular follow-up appointments and possibly repeat endoscopy may be necessary to assess the healing of your esophagus and adjust your treatment plan accordingly.
In terms of managing your symptoms, it is crucial to maintain a diet that avoids trigger foods, such as spicy or acidic foods, caffeine, and large meals. Eating smaller, more frequent meals can also help reduce reflux symptoms. Additionally, elevating the head of your bed and avoiding lying down immediately after eating can be beneficial.
As for the skin reactions you mentioned, such as hives, it is essential to discuss these with your healthcare provider. While they may not be directly related to the PPI, they could indicate an allergic reaction or sensitivity to a medication or food. Your doctor may recommend allergy testing or adjusting your medication regimen to address these symptoms.
In conclusion, while C-level GERD and esophagitis can be concerning, they are manageable conditions. With appropriate treatment, including the use of PPIs, dietary modifications, and regular medical follow-up, many patients experience significant improvement. If you have ongoing concerns about your symptoms or the duration of your PPI therapy, do not hesitate to discuss them with your healthcare provider. They can provide personalized recommendations based on your specific situation and help you navigate the complexities of managing GERD and esophagitis effectively.
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