Exploring the Connection Between Premature Contractions and Acid Reflux - Cardiology

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Premature contractions and their association with gastroesophageal reflux disease (GERD)?


Hello Director Wu, I have organized my questions for easier narration and reading:
1.
I have undergone myocardial perfusion imaging and echocardiography in the cardiology department, both of which showed no abnormalities.
However, a 24-hour Holter monitor detected some missed beats, which the physician said are still within a safe range.
2.
Most days I feel fine, but occasionally I experience missed beats, usually in the evening or after dinner.
It can happen several times within a minute or may occur a few minutes apart.
If I intentionally cough during these episodes, it seems to return to normal.
3.
Sometimes, when I feel a stronger missed beat, it triggers intense nausea, and I might even vomit a little bit of stomach contents, but I do not feel any acidity or heat.
In such situations, I find myself wishing to vomit because it seems that doing so might resolve the missed beats.
4.
I have undergone an esophagogastroduodenoscopy in the gastroenterology department, and the physician indicated that there were no abnormalities found.
I was advised to monitor and adjust my diet and habits, but no medication was prescribed.
5.
Director Wu, could my situation possibly be related to gastroesophageal reflux disease (GERD) or premature ventricular contractions (PVCs)? Is there a potential connection between the two?
6.
The missed beats are very rarely located in the middle-left area; they are almost always about 1.5 inches above the xiphoid process.
7.
Occasionally, medications like antiarrhythmics are ineffective.
For reflux, I have tried over-the-counter proton pump inhibitors (PPIs) with no effect, but imported PPIs seem to help suppress the symptoms.
However, after stopping the medication, the aforementioned issues tend to recur after about one to two months.
I have many questions, and I hope you can take the time to clarify these issues for me.
Thank you.

Mr. Zhang, 50~59 year old female. Ask Date: 2021/06/04

Dr. Wu Xueming reply Cardiology


Many factors in daily life can contribute to this condition, such as emotions, stress, irregular sleep patterns, or excessive intake of caffeinated beverages.
It is recommended to adjust your lifestyle and engage in regular exercise.
For gastroesophageal reflux, it is advisable to consult a gastroenterologist to investigate medication options.
If palpitations persist, it is still recommended to visit a hospital for a physician to adjust the medication.

Reply Date: 2021/06/04

More Info


The connection between premature contractions (also known as premature ventricular contractions or PVCs) and acid reflux (gastroesophageal reflux disease, GERD) is a topic of interest in the medical community. While both conditions can occur independently, there is evidence suggesting that they may be related in some patients.

1. Understanding Premature Contractions: PVCs are extra heartbeats that originate in the ventricles. They can cause a sensation of a skipped heartbeat or a fluttering feeling in the chest. PVCs are often benign, especially in individuals without underlying heart disease. Factors such as stress, caffeine, alcohol, and certain medications can trigger these contractions. In your case, the fact that you have undergone thorough cardiac evaluations (including myocardial perfusion imaging and echocardiograms) and that your 24-hour Holter monitor showed some missed beats within a safe range suggests that your PVCs may not be of significant concern.

2. Acid Reflux and Its Symptoms: GERD occurs when stomach acid flows back into the esophagus, leading to symptoms such as heartburn, regurgitation, and sometimes nausea. The sensation of nausea and the urge to vomit that you experience, especially after meals, could be related to acid reflux. The fact that you feel relief after vomiting may indicate that the contents of your stomach are irritating your esophagus or that the pressure in your stomach is affecting your diaphragm and, consequently, your heart rhythm.

3. Possible Connection Between PVCs and GERD: There are a few theories as to how GERD might contribute to the sensation of PVCs. One possibility is that the irritation of the esophagus from acid reflux can stimulate the vagus nerve, which plays a role in heart rate regulation. This stimulation could potentially lead to the occurrence of PVCs. Additionally, the discomfort from acid reflux may cause anxiety or stress, which can further exacerbate PVCs.

4. Timing of Symptoms: You mentioned that your PVCs often occur in the evening or after meals. This timing could correlate with your eating habits and the potential for increased acid production or reflux after eating. If you are experiencing heavy meals or lying down shortly after eating, this could contribute to both your reflux symptoms and the sensation of PVCs.

5. Management Strategies: Since you have already consulted with a gastroenterologist and undergone an endoscopy without significant findings, it may be beneficial to focus on lifestyle modifications. These can include:
- Eating smaller, more frequent meals to reduce stomach pressure.

- Avoiding trigger foods that may exacerbate acid reflux (such as spicy foods, caffeine, and alcohol).

- Elevating the head of your bed to prevent nighttime reflux.

- Managing stress through relaxation techniques, as stress can exacerbate both PVCs and GERD symptoms.

6. Medication Considerations: You mentioned that over-the-counter PPIs (proton pump inhibitors) have not been effective, while imported PPIs seem to provide some relief. It may be worthwhile to discuss this with your healthcare provider, as they can help determine the best course of treatment. Additionally, if your PVCs are bothersome, your doctor may consider adjusting your heart rhythm medication or exploring other options.

7. When to Seek Further Evaluation: If your symptoms persist or worsen, or if you experience new symptoms such as chest pain, shortness of breath, or significant changes in your heart rhythm, it is crucial to seek medical attention promptly. Continuous monitoring and follow-up with both your cardiologist and gastroenterologist will help ensure that both conditions are managed effectively.

In summary, while there may be a connection between your premature contractions and acid reflux, it is essential to approach the management of both conditions holistically. Lifestyle modifications, dietary changes, and ongoing communication with your healthcare providers will be key in addressing your symptoms and improving your overall quality of life.

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