Proliferative Vitreoretinopathy and Its Impact on Vision - Ophthalmology

Share to:

Retinal laser therapy


Hello, Director Gao.
I apologize for asking you again about proliferative vitreoretinopathy (PVR): it is a complication following surgery for retinal detachment with tears.
It is commonly seen in cases of excessive cryotherapy, large tears, multiple retinal tears, long-standing rhegmatogenous retinal detachment, and multiple intraocular surgeries.
PVR is the main reason for the failure of retinal detachment repair surgery.
The pathophysiology of PVR essentially involves an excessive reparative response of ocular tissue to injury.
Retinal pigment epithelial (RPE) cells migrate, proliferate, and undergo transformation from the site of the tear, potentially converting into fibroblast-like cells that secrete collagen.
RPE cells can also express and secrete various inflammatory factors and growth factors, attracting more cells to migrate and proliferate.
This leads to the formation of cellular proliferative membranes on the anterior and posterior surfaces of the retina and the posterior vitreous.
The contraction of these membranes can cause tractional retinal detachment, resulting in retinal stiffness, shortening, and eventual loss of function.
1.
In your response to the online user, I saw this link.
After my retinal laser treatment, I developed a significant number of floaters.
Could this be due to excessive energy from cryotherapy leading to proliferative vitreoretinopathy?
2.
Is retinal photocoagulation the same as retinal laser treatment?
3.
Is one of the symptoms of proliferative vitreoretinopathy the occurrence of numerous floaters?
4.
Currently, I am experiencing very severe floaters.
Could these floaters lead to tractional retinal detachment, especially as they seem to catch on the retina with every movement of my eye?
5.
I had a dilated fundus examination at Tong Hospital last week, but I forgot to ask the doctor whether I have this issue.
Does the absence of information from the doctor mean that I do not have this problem? [Dr.
Li performed the dilated fundus examination, checking various quadrants, but I did not hear him mention examining the vitreous.
He is a very good doctor.]
6.
I would like to ask if the pan-retinal laser treatment for diabetes is the same as the laser treatment for retinal degeneration, aside from the area treated? I have found very few articles online mentioning severe floaters occurring after laser treatment, and it seems that diabetic laser treatment involves the entire retina, while I only had peripheral treatment [about 300 shots].
Why is it so severe?
7.
Previously, Dr.
Li at Tong Hospital mentioned that my retinal degeneration is approximately the size of 2 clock hours.
Is this considered large or small? Is it normal to have 200-300 laser shots? Thank you very much, doctor.

Danxin de ren, 20~29 year old female. Ask Date: 2021/06/05

Dr. Gao Pilin reply Ophthalmology


Hello, concerned individual:
1.
I apologize, but this cannot be determined.

2.
No, please refer to https://reurl.cc/gWzz0p.

3.
It should not be a problem.

4.
The vitreous does not require special examination; if there are issues, they will be observed during the retinal examination.

5.
The functions are different.

6.
It is not considered small.
The number of laser treatments is normal, and sometimes there are more.
Answers found online can only serve as a reference; if necessary, it is still important to seek medical attention at a healthcare facility.
I hope to have the opportunity to assist you.

Best regards,
Gao Pilin

Reply Date: 2021/06/05

More Info


Proliferative Vitreoretinopathy (PVR) is a significant complication that can arise after retinal detachment surgery, particularly in cases involving extensive retinal tears or multiple surgeries. It is characterized by an abnormal healing response where retinal pigment epithelial (RPE) cells migrate, proliferate, and transform into fibroblast-like cells, leading to the formation of cellular membranes on the retinal surface. This can result in tractional retinal detachment, which may severely impact vision.

1. Post-Surgery Complications and Symptoms: After undergoing retinal laser treatment, it is not uncommon for patients to experience an increase in floaters, which can be attributed to the changes in the vitreous gel and the potential development of PVR. The strong energy used in laser treatments can indeed contribute to the proliferation of these cells, leading to the symptoms you are experiencing. Floaters are often a result of the vitreous gel pulling away from the retina, and in cases of PVR, the presence of membranes can exacerbate this condition.

2. Understanding Retinal Laser Treatments: Retinal photocoagulation, often referred to as laser treatment, is a procedure used to treat various retinal conditions, including diabetic retinopathy and retinal tears. It involves using laser energy to create small burns in the retina, which helps to seal leaks and prevent further detachment. The term "electrocoagulation" generally refers to a different technique that uses electrical current rather than laser energy.

3. Symptoms of PVR: One of the symptoms associated with PVR is indeed an increase in floaters. These floaters can appear as spots, cobwebs, or strands in your vision, and they may become more pronounced as the condition progresses. If you are experiencing a significant increase in floaters, it is essential to monitor this closely, as it may indicate changes in the vitreous or the development of PVR.

4. Risk of Tractional Retinal Detachment: The concern regarding floaters causing tractional retinal detachment is valid. If the vitreous gel is pulling on the retina, it can lead to tears or detachment. However, not all floaters will cause this issue. It is crucial to have regular follow-ups with your ophthalmologist to assess the condition of your retina and vitreous.

5. Follow-Up and Diagnosis: If your ophthalmologist did not mention PVR during your last examination, it may suggest that they did not observe any signs of this condition. However, if you continue to experience significant floaters or other visual disturbances, it is advisable to seek a second opinion or request a more thorough examination, including a detailed assessment of the vitreous.

6. Comparison of Laser Treatments: The laser treatments for diabetic retinopathy and retinal degeneration may differ in technique and application. Diabetic laser treatment often involves treating a larger area of the retina to prevent further damage, while treatments for retinal tears may focus on specific areas. The number of laser spots used can vary based on the extent of the condition being treated. Your experience of having around 300 laser spots is not uncommon for certain conditions, but the severity of floaters following treatment can vary from person to person.

In conclusion, if you are experiencing significant changes in your vision, including an increase in floaters or any other symptoms, it is crucial to maintain open communication with your eye care provider. Regular monitoring and follow-up examinations are essential to ensure that any potential complications, such as PVR, are identified and managed promptly. If you have concerns about your current symptoms or the implications of your previous treatments, do not hesitate to seek further evaluation.

Similar Q&A

Understanding Vitreous Opacity: Causes and Effects on Vision

Hello, doctor. I would like to ask another question. Vitreous opacities are a common sign of vitreous diseases. Proliferation of vitreous fibrous tissue, primarily manifested as the formation of fibrous membranes or strands within the vitreous, can often be associated with the re...


Dr. Gao Pilin reply Ophthalmology
Hello, concerned individual: Floaters, or myodesopsia, are related to the proliferation of vitreous fibers. It cannot be definitively concluded whether they are associated with laser treatment; what can be confirmed is that this is a degeneration of the vitreous body, which may b...

[Read More] Understanding Vitreous Opacity: Causes and Effects on Vision


Understanding Photopsia and Vitreous Degeneration: Eye Health Concerns

Hello, Doctor Gao. I have myopia in both eyes, with the right eye at -5.25 diopters and the left eye at -6.25 diopters. I have been experiencing floaters for three years. I would like to ask you the following questions: 1. I started experiencing photopsia at the beginning of la...


Dr. Gao Pilin reply Ophthalmology
Hello: 1. Photopsia and Retinal Detachment: Photopsia may be related to retinal issues, but the specific extent of its impact on the retina and optic nerve requires further evaluation. Retinal detachment may increase the risk of glaucoma, but it does not necessarily lead to gla...

[Read More] Understanding Photopsia and Vitreous Degeneration: Eye Health Concerns


Understanding Vitreous Proliferative Disorders: Are Long Floaters a Concern?

Hello, Dr. Gao. From your response, I would like to confirm one thing: the manifestation of vitreous proliferative disease does not include the phenomenon of floaters becoming longer, correct? Therefore, if floaters are becoming longer, it should not indicate any malignant change...


Dr. Gao Pilin reply Ophthalmology
Hello, Fei: 1. The vitreous body itself does not undergo proliferative changes; it only experiences natural degenerative changes, which can lead to the phenomenon of floaters. Treatment is not necessary unless there is involvement with the retina, such as the occurrence of hole...

[Read More] Understanding Vitreous Proliferative Disorders: Are Long Floaters a Concern?


Understanding Retinal Proliferation: Concerns and Treatment Options

Hello Dr. Wang, my mother has been experiencing frequent falls while walking and has always felt that her vision is poor. Last week, she sought medical attention due to redness and swelling in her eyes, and during a vision check, it was found that her corrected vision in the righ...


Dr. Wang Zhangji reply Ophthalmology
Hello: Proliferative retinopathy is more commonly seen in patients with diabetes. Fluorescein angiography is not a surgical procedure; it is a diagnostic test that uses a contrast agent. Although there is a potential for serious side effects, the likelihood is very low. Retinal d...

[Read More] Understanding Retinal Proliferation: Concerns and Treatment Options


Related FAQ

Vitreous Degeneration

(Ophthalmology)

Retinal Disease

(Ophthalmology)

Vision

(Ophthalmology)

Vitrectomy Surgery

(Ophthalmology)

Vascular Proliferation

(Ophthalmology)

Macular Pucker

(Ophthalmology)

Vitreous Liquefaction

(Ophthalmology)

Visual Disturbance

(Ophthalmology)

Posterior Vitreous Detachment

(Ophthalmology)

Retinal Laser Treatment

(Ophthalmology)