How Soon Can You Conceive After Receiving the AZ Vaccine?

Fertility preparation issues

If my wife, who is a healthcare worker, receives the AstraZeneca (AZ) vaccine, how long should we wait before trying to conceive? I've heard that one should wait six months after vaccination before attempting to get pregnant.
However, my wife is already 35 years old, and we previously experienced a miscarriage due to chromosomal issues.
We were considering in vitro fertilization (IVF) with preimplantation genetic screening (PGS) for a safer option.
The current pandemic has made me feel that it is necessary for her to get vaccinated, but I am also concerned about her age.
Waiting could potentially delay our plans by six months to a year, and I am unsure of what to do.
Should we consult a hospital about proceeding with IVF and PGS after she receives the AZ vaccine? However, I am hesitant to visit a hospital during the pandemic.
I would appreciate any advice from a doctor regarding whether it is advisable to wait six months after the second dose before pursuing IVF.

Niming, 30~39 year old female. Ask Date: 2021/06/06

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, most vaccines are generally recommended to wait for three months after completion before trying to conceive.
Regarding the AZ vaccine, I am not an expert in this area, and you may need to consult other specialists.
Wishing you good health.

Reply Date: 2021/06/06

More Info

When considering conception after receiving the AstraZeneca (AZ) vaccine, it's important to understand the current medical guidelines and research surrounding this topic. Generally, most health authorities recommend that individuals can conceive shortly after vaccination, and there is no strict requirement to wait for an extended period, such as six months, before trying to conceive.
The primary concern regarding vaccination and pregnancy revolves around ensuring that the vaccine does not adversely affect fertility or pregnancy outcomes. Studies conducted so far have not indicated any negative impact of COVID-19 vaccines, including the AZ vaccine, on fertility or pregnancy. In fact, the Centers for Disease Control and Prevention (CDC) and other health organizations encourage vaccination for those who are planning to conceive, as the benefits of vaccination in preventing severe illness from COVID-19 outweigh potential risks.

In your specific situation, where your wife is a healthcare worker and has already experienced a miscarriage due to chromosomal issues, it is understandable that you are concerned about the timing of conception after vaccination. Given her age (35 years), it is crucial to consider both her health and the potential risks associated with delaying pregnancy. The age factor can influence fertility and the risk of complications during pregnancy, so it is advisable not to postpone conception unnecessarily.

If your wife has received both doses of the AZ vaccine, she can start trying to conceive soon after completing the vaccination series. The general recommendation is to wait at least a few weeks after the second dose to allow her immune system to respond fully to the vaccine, but this does not mean she has to wait for months. Many healthcare providers suggest that waiting for one menstrual cycle after vaccination is a reasonable approach, allowing the body to adjust and ensuring that any vaccine-related side effects have resolved.

Regarding your interest in assisted reproductive technologies like in vitro fertilization (IVF) with preimplantation genetic screening (PGS), it is advisable to consult with a fertility specialist. They can provide personalized guidance based on your wife's health history, vaccination status, and any other relevant factors. While the pandemic may complicate in-person visits, many clinics offer telehealth consultations, which can be a convenient way to discuss your concerns without the need for an immediate in-person visit.

In summary, there is no need to wait for six months after receiving the AZ vaccine to conceive. It is generally safe to try for pregnancy shortly after vaccination, especially if both doses have been administered. However, consulting with a fertility specialist can provide you with tailored advice and help you navigate your options, including the potential for IVF and PGS. Prioritize your wife's health and well-being, and make informed decisions based on the latest medical guidance.

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