Cycloplegic Agent Concentrations for Myopia Management - Ophthalmology

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What is the concentration of mydriatic agents?


Hello Dr.
Wang,
My child is currently 9 years old and has a myopia of -1.75 diopters.
The ophthalmologist has recommended using a cycloplegic agent to slow the progression of myopia, with a prescribed concentration of 0.25%.
A colleague's child, who is 11 years old, has a myopia of -5.00 diopters, and a different doctor also prescribed a cycloplegic agent at the same concentration of 0.25%.

Could you please advise whether different degrees of myopia require different concentrations of cycloplegic agents? At what degree of myopia is a concentration of 0.25% appropriate? And at what degree of myopia is a concentration of 0.5% suitable? Are there any adverse effects associated with using an inappropriate concentration?
Best regards!

Hank, 30~39 year old female. Ask Date: 2003/04/02

Dr. Wang Zhangji reply Ophthalmology


Hello! The concentration of mydriatic agents is not solely based on the degree of refractive error but rather should be adjusted according to the individual's constitution and their response to the medication.
If your child has been using 0.25% for a period of time and their prescription is stable, it is recommended to try using 0.1% for treatment.
Best wishes for health from Dr.
Wang Zhang-ji, Ophthalmology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2003/04/02

More Info


Dear Inquirer,
Thank you for your question regarding the use of cycloplegic agents for myopia management in children. It’s great to see that you are actively seeking information to help manage your child’s vision health.
Cycloplegic agents, such as atropine and cyclopentolate, are commonly used in the management of myopia (nearsightedness) to temporarily paralyze the ciliary muscle of the eye, which helps to relax accommodation. This can potentially slow the progression of myopia in children. The concentration of the cycloplegic agent used can vary based on the individual needs of the patient, their age, and the degree of myopia.

In your case, both your child with -1.75 diopters and your colleague's child with -5.00 diopters are being prescribed a cycloplegic agent at a concentration of 0.25%. This concentration is often used as a starting point for myopia management in children, especially for those with lower to moderate levels of myopia. The choice of concentration may not solely depend on the degree of myopia but also on the child's age, their response to treatment, and the specific recommendations of the eye care professional.

For children with higher degrees of myopia, such as -5.00 diopters, some practitioners may consider using a higher concentration, such as 0.5% or even 1% atropine, depending on the clinical judgment and the specific treatment goals. Higher concentrations may provide a more pronounced effect in slowing myopia progression, but they also come with an increased risk of side effects, such as increased light sensitivity, blurred vision, and potential systemic absorption leading to side effects like dry mouth or increased heart rate.

Using an inappropriate concentration can lead to inadequate control of myopia progression or increased side effects. For instance, if a child with significant myopia is treated with a lower concentration that does not effectively manage their condition, they may continue to experience worsening vision. Conversely, using a higher concentration than necessary may lead to discomfort and side effects that could discourage adherence to treatment.

In summary, while the 0.25% concentration is commonly used, the decision to use a specific concentration should be tailored to the individual child’s needs, taking into account their age, the degree of myopia, and their overall health. Regular follow-ups with the eye care provider are essential to monitor the effectiveness of the treatment and make any necessary adjustments.

It is crucial to have open communication with your child's eye doctor to discuss any concerns regarding the concentration of the cycloplegic agent and to ensure that the treatment plan is optimal for your child's specific situation.
Best regards, and I wish you and your child the best in managing their vision health!

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