Sudden Increases in Eye Pressure: Causes and Concerns - Ophthalmology

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What are the causes of a sudden increase in intraocular pressure?


Hello Doctor: In May 2019, during my health check-up, my intraocular pressure (IOP) was 14 mmHg in the left eye and 16 mmHg in the right eye, with no previous abnormalities noted.
However, in April 2020, my IOP was found to be 22 mmHg in the left eye and 24 mmHg in the right eye, and I exhibited symptoms of optic nerve atrophy.
The doctor diagnosed me with "pre-glaucoma" (visual field VFI 98%, OCT average 92 µm in the left eye, 103 µm in the right eye).
I was prescribed eye drops (latanoprost) for a year, and my IOP initially decreased to 17 mmHg in the left eye and 18 mmHg in the right eye.
In June 2020, the measurements were 22 mmHg in the left eye and 25 mmHg in the right eye.
In January 2021, the IOP was 22 mmHg in the left eye and 23 mmHg in the right eye.
Three months later, in April, the recheck showed 21 mmHg in the left eye and 22 mmHg in the right eye.
The doctor switched my medication to brimonidine.
In May, the recheck showed 21 mmHg in the left eye and 22 mmHg in the right eye, with no significant improvement.
The doctor advised me to continue the eye drops for another month, and if the results remain the same, we would consider changing the medication again.
So far, the OCT and fundus examinations are similar to those at the time of diagnosis.
I would like to ask: 1.
What could have caused such a sudden increase in IOP from May 2019 to April 2020 in just a few months? (For example: excessive eye strain, etc.?) I am really worried that it could be some difficult-to-treat glaucoma, especially since I am only 27 years old...
2.
Is it possible for such a significant change in the optic nerve to occur in such a short time, even if the IOP was just above 20 mmHg in May 2019? (Considering the difference between the two eyes) 3.
Given my current situation, what is the likelihood of needing surgery, since the eye drops do not seem to be effective for me? Or is it possible that my IOP is continuing to rise without my knowledge?

Sam, 20~29 year old female. Ask Date: 2021/06/15

Dr. He Jianxian reply Ophthalmology


Based on your clinical data, there is no significant atrophy observed in the left eye, and it is unclear whether there are any visual field defects.
If there are no defects, I believe it would be reasonable to simply monitor the situation without medication.
Prolonged use of the same medication can lead to diminished efficacy in some individuals, and in such cases, a change in medication may be necessary.
I think you might even consider discontinuing the medication and monitoring for a period of time, as your intraocular pressure is not particularly high, and there are no obvious signs of damage to the optic nerve.
The above suggestions are for your reference.
Dr.
He Jianxian, Ophthalmology, Nantou Hospital.

Reply Date: 2021/06/15

More Info


Understanding sudden increases in eye pressure is crucial, especially for individuals with a history of eye conditions like glaucoma. Your situation, characterized by a significant rise in intraocular pressure (IOP) from 2019 to 2020, raises several important questions regarding potential causes, implications for vision, and treatment options.

1. Possible Causes of Sudden Increase in Eye Pressure: The sudden increase in your eye pressure from 14 mmHg and 16 mmHg in May 2019 to 22 mmHg and 24 mmHg in April 2020 could be attributed to several factors. One common cause is increased aqueous humor production or decreased outflow, which can be influenced by various factors, including genetics, age, and environmental conditions. Additionally, lifestyle factors such as prolonged screen time, inadequate breaks during visual tasks, and even stress can contribute to elevated IOP. In some cases, underlying conditions like inflammation or changes in the eye's anatomy can also lead to increased pressure. It’s essential to consider that even minor changes in the eye's drainage system can significantly impact IOP, especially in individuals predisposed to glaucoma.

2. Impact of Eye Pressure on Vision: The concern about whether a rise in eye pressure can lead to significant changes in the optic nerve and vision is valid. The optic nerve is sensitive to pressure changes, and even a few mmHg can have a substantial impact over time, especially in someone with a predisposition to glaucoma. The fact that you have experienced optic nerve changes (indicated by the diagnosis of "pre-glaucoma") suggests that your optic nerve is already under stress. The difference in pressure between your eyes and the observed changes in the left eye could be due to individual anatomical differences or variations in how each eye responds to pressure changes. Regular monitoring and imaging tests like OCT (Optical Coherence Tomography) are crucial in assessing the health of your optic nerve and detecting any progressive damage.

3. Treatment Options and Surgical Considerations: Regarding your current treatment with eye drops, it’s not uncommon for patients to experience varying degrees of effectiveness with different medications. If your eye pressure remains elevated despite treatment, your ophthalmologist may consider alternative medications or even surgical options. Surgical interventions, such as trabeculectomy or minimally invasive glaucoma surgeries, can be effective in lowering IOP when medications fail. However, the decision to proceed with surgery typically depends on several factors, including the degree of pressure elevation, the health of the optic nerve, and your overall eye health. It’s essential to maintain open communication with your eye care provider about your concerns and treatment efficacy.

In conclusion, while the rise in your eye pressure is concerning, it is essential to approach this condition with a comprehensive management plan. Regular follow-ups with your ophthalmologist, adherence to prescribed treatments, and lifestyle modifications (like reducing screen time and ensuring proper eye rest) can help manage your eye health effectively. Additionally, educating yourself about glaucoma and its implications can empower you to take an active role in your treatment and monitoring. Remember, early detection and intervention are key in preserving vision and preventing further complications.

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