Should My 81-Year-Old Grandfather with Heart Issues Get the AZ Vaccine? - Cardiology

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Should I get the AstraZeneca vaccine or not?


My grandfather is 81 years old and has been suffering from diabetes for nearly forty years.
For the past ten years, he has been taking medications for cardiovascular diseases.
In March of this year, due to severe blockage and calcification of the coronary arteries, he had two stents placed.
Currently, he is taking the following medications: 1.
Apixaban 2.5 mg twice daily, 2.
Cardizem 100 mg twice daily, 3.
Concor 1.25 mg once daily, 4.
Lipitor 40 mg once daily, 5.
Urokinase 25 mg once daily, 6.
Clopidogrel 75 mg once daily, 7.
Glimepiride 25 mg once daily, 8.
Insulin injection (NovoMix 30) 16 units in the morning and 16 units in the evening.

I would like to consult a physician regarding whether a patient with heart failure like him should receive the AZ vaccine.
The family has been very anxious these past few days and is unsure of what to do.

Bu zhi suo cuo, 30~39 year old female. Ask Date: 2021/06/18

Dr. He Dongjin reply Cardiology


Hello, in principle, the benefits of receiving the AZ vaccine outweigh the risks for older adults, many of whom have chronic diseases.
As long as their condition is stable, with minimal fluctuations in blood pressure, heart rate, and blood sugar levels, and without symptoms such as shortness of breath, edema, or bruising, and no significant contraindications, it is still advisable to get vaccinated.
Peaceful Changhua Hospital cares about you.

Reply Date: 2021/06/18

More Info


When considering whether your 81-year-old grandfather with heart issues should receive the AstraZeneca (AZ) COVID-19 vaccine, it is essential to weigh the risks and benefits carefully. Given his medical history, including long-standing diabetes and recent coronary artery disease requiring stent placement, he is indeed in a high-risk category for severe complications from COVID-19.
The primary concern regarding the AZ vaccine has been its association with rare thrombotic events, particularly in younger populations. However, studies have shown that the benefits of vaccination, especially in older adults and those with underlying health conditions, far outweigh the risks of these rare side effects. In fact, the risk of severe outcomes from COVID-19, including hospitalization, long-term complications, and death, is significantly higher in older adults and those with cardiovascular diseases than the risk of vaccine-related complications.

Your grandfather's current medications, which include anticoagulants and medications for heart failure, do not contraindicate the use of the AZ vaccine. In fact, patients on anticoagulants have been vaccinated safely. It is crucial, however, to ensure that his healthcare provider is aware of all his medications and health conditions before vaccination. This allows for proper monitoring and management of any potential side effects.

The AZ vaccine has been shown to provide substantial protection against COVID-19, including severe disease and hospitalization. The vaccine's efficacy in older populations is comparable to that of mRNA vaccines, such as Pfizer-BioNTech and Moderna. Given that your grandfather is already at risk for severe complications from COVID-19 due to his age and underlying health conditions, vaccination is strongly recommended.

In terms of timing regarding his medications, there is generally no need to stop any of his medications before or after receiving the vaccine. However, it is advisable to consult with his healthcare provider for personalized guidance. They may recommend monitoring his blood pressure and heart rate closely after vaccination, especially since he has a history of heart issues.

In summary, your grandfather should receive the AZ vaccine. The risk of severe complications from COVID-19 far exceeds the potential risks associated with the vaccine, especially considering his age and health status. Vaccination will not only protect him but also contribute to the broader public health effort to control the pandemic. It is essential to maintain open communication with his healthcare provider to ensure that he receives the best possible care throughout this process.

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