Choroidal Neovascularization: Eylea Treatment and Recovery Tips - Ophthalmology

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Choroidal neovascularization


Hello, doctor.
I have high myopia that has led to the proliferation of blood vessels in the macula.
Three days ago, I received an Eylea injection treatment, and the doctor informed me that the medication may take 1 to 2 weeks to take effect.
I would like to understand the expected efficacy and the timeline for the medication to become effective.
Additionally, are there any post-operative care recommendations or specific foods or nutrients I should consider? Thank you.

Niming, 30~39 year old female. Ask Date: 2021/06/20

Dr. He Jianxian reply Ophthalmology


The efficacy of this medication is expected to diminish within a month.
Therefore, if the condition recurs, it will be necessary to administer another dose after one month.
The effectiveness should be quite good, as it will promote the regression of neovascularization.
While the exact onset time of the medication's effects is difficult to estimate, it is reasonable to expect that changes will occur within one to two weeks.
There are no specific nutritional recommendations; a balanced diet without selective eating is advised.
Dr.
Ho Chien-Hsien, Department of Ophthalmology, Nantou Hospital.

Reply Date: 2021/06/20

More Info


Choroidal neovascularization (CNV) is a condition characterized by the growth of new blood vessels in the choroid layer of the eye, often associated with conditions such as age-related macular degeneration (AMD) and high myopia. In your case, it appears that your CNV is a result of high myopia, which can lead to significant vision impairment if not treated properly.

Eylea (aflibercept) is an anti-VEGF (vascular endothelial growth factor) medication that is commonly used to treat CNV. It works by inhibiting the action of VEGF, a protein that promotes the growth of abnormal blood vessels in the eye. By blocking VEGF, Eylea helps to reduce the leakage of fluid and blood from these abnormal vessels, thereby stabilizing or improving vision.


Expected Efficacy and Onset of Action
After receiving an Eylea injection, it is typical for patients to notice improvements in vision or a reduction in fluid accumulation within 1 to 2 weeks. However, the full therapeutic effect may take longer to manifest, and some patients may require multiple injections over time to achieve optimal results. It is essential to follow up with your ophthalmologist to monitor your condition and determine if additional treatments are necessary.


Post-Injection Care and Nutritional Support
Following your Eylea injection, there are several recommendations to ensure optimal recovery and support your eye health:
1. Rest and Recovery: It is advisable to rest your eyes after the injection. Avoid strenuous activities and protect your eyes from bright lights and screens for the first 24 hours.

2. Monitor for Symptoms: Keep an eye out for any unusual symptoms such as increased pain, redness, or changes in vision. If you experience any of these, contact your healthcare provider immediately.

3. Nutrition: A healthy diet can support overall eye health. Consider incorporating the following nutrients:
- Omega-3 Fatty Acids: Found in fish like salmon and flaxseeds, omega-3s may help reduce inflammation and support retinal health.

- Antioxidants: Foods rich in vitamins C and E, such as citrus fruits, nuts, and leafy greens, can help protect your eyes from oxidative stress.

- Lutein and Zeaxanthin: These carotenoids, found in green leafy vegetables like spinach and kale, are known to support macular health.

- Zinc: This mineral is important for maintaining the health of the retina and can be found in foods like beans, nuts, and whole grains.

4. Hydration: Staying well-hydrated is crucial for overall health, including eye health. Aim to drink plenty of water throughout the day.

5. Regular Check-Ups: Schedule regular follow-up appointments with your ophthalmologist to monitor your condition and the effectiveness of the treatment. This will help in making timely adjustments to your treatment plan if necessary.

6. Lifestyle Modifications: If you smoke, consider quitting, as smoking can exacerbate eye conditions. Additionally, managing other health conditions, such as hypertension and diabetes, is vital for maintaining eye health.


Conclusion
In summary, Eylea is an effective treatment for choroidal neovascularization, particularly in cases related to high myopia. While you may begin to notice improvements within a week or two, ongoing monitoring and possibly additional treatments may be necessary. Supporting your recovery with a balanced diet rich in eye-healthy nutrients, staying hydrated, and maintaining regular follow-up appointments will contribute to the best possible outcomes for your vision. Always consult your healthcare provider for personalized advice and recommendations tailored to your specific situation.

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