Autoimmune Thyroiditis: Medication Effects and Specialist Care - Internal Medicine

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Autoimmune diseases


Hello, Doctor.
I have autoimmune thyroiditis and have been taking Methimazole and Levothyroxine for over a year.
I also have a history of hyperthyroidism, but I have not taken medication for over 15 years.
My thyroid-related indices have been regularly monitored, and the results have been good.
However, in my most recent blood test on June 5, my results were TSH: 0.03, T3: 92, and T4: 1.87.
Could this be related to the medications I am taking? Additionally, I have been seeing a rheumatologist for over a year.
If my condition is due to hyperthyroidism, should I be consulting both an endocrinologist and a rheumatologist? Thank you for your patience in reading this, and I look forward to your response.
Thank you.

Amy, 50~59 year old female. Ask Date: 2021/06/22

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your message.
Here is my response: 1.
There should be no correlation between the use of Dexamethasone, Bilastine, and thyroid dysfunction.
2.
If there have been recent abnormalities in thyroid function but no symptoms are present, you may consider asking your physician to monitor thyroid function again during the next examination.
If abnormalities persist, it is advisable to consult an endocrinologist for confirmation; however, if you are currently experiencing symptoms similar to hyperthyroidism, it is recommended to follow up with the endocrinology clinic as soon as possible.
The Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare, is concerned about your health.

Reply Date: 2021/06/22

More Info


Autoimmune thyroiditis, commonly known as Hashimoto's thyroiditis, is a condition where the immune system mistakenly attacks the thyroid gland, leading to inflammation and often resulting in hypothyroidism. In your case, you have a history of hyperthyroidism and have been on medications such as Carbimazole (驅異樂) and Prednisone (必賴克廔) for over a year. Your recent lab results indicate a suppressed TSH level (0.03) and normal T3 and T4 levels, which suggest that your thyroid function may be in a hyperthyroid state again.

Regarding your question about whether the medications could be related to your thyroid function, it is important to note that Carbimazole is typically used to treat hyperthyroidism by inhibiting thyroid hormone production. However, prolonged use of corticosteroids like Prednisone can have various effects on the body, including potential impacts on the immune system and thyroid function. While it is less common for these medications to directly cause hyperthyroidism, they can influence the overall hormonal balance in the body. Therefore, it is advisable to discuss these results with your healthcare provider, who can evaluate the potential relationship between your medications and thyroid function.

As for your ongoing care, it is crucial to have a multidisciplinary approach when dealing with autoimmune conditions and thyroid issues. Since you have been seeing a rheumatologist for your autoimmune thyroiditis, it may be beneficial to also consult an endocrinologist, particularly one specializing in thyroid disorders. This specialist can provide a more focused evaluation of your thyroid function and help determine the best course of action, including whether any adjustments to your current medications are necessary.

In summary, while your current medications may not be the direct cause of your altered thyroid function, they could be influencing your overall health status. It is essential to have regular follow-ups with both your rheumatologist and an endocrinologist to monitor your condition closely. This collaborative care will ensure that all aspects of your health are addressed, especially considering the complexities of autoimmune diseases and their treatment. Regular blood tests to monitor thyroid function, along with a thorough assessment of your symptoms, will guide your healthcare team in making informed decisions about your treatment plan.

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