Posterior Capsule Opacity: Is It Linked to the COVID Vaccine? - Ophthalmology

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Posterior capsule opacification


Is this related to receiving the AZ vaccine? I visited an ophthalmology clinic for an eye examination on April 16, and the doctor did not mention anything at that time.
After receiving the vaccine on May 17, I started to notice blurred vision.
I returned for another examination yesterday, and the doctor said there is posterior capsule opacification and recommended laser treatment.
If this is not related to the vaccine, could the opacification have developed over time? What is the treatment method? How many sessions are needed? Will it happen again? How can it be prevented? Thank you.

Obasan, 60~69 year old female. Ask Date: 2021/06/23

Dr. Cai Wenyuan reply Ophthalmology


If the diagnosis is accurate, it should not be related to the vaccine.

Reply Date: 2021/06/23

More Info


Posterior capsule opacity (PCO), also known as secondary cataract, is a common condition that can occur after cataract surgery. It happens when the thin membrane (posterior capsule) that holds the lens in place becomes cloudy, leading to blurred vision. This condition is typically not linked to vaccinations, including the COVID-19 vaccines such as AstraZeneca (AZ).
To address your specific concerns regarding the potential relationship between the AZ vaccine and the development of PCO, it is important to understand that PCO is primarily a result of the natural healing process following cataract surgery. The cells that are left behind during the surgery can proliferate and cause the capsule to become cloudy over time. This process can occur months or even years after the initial surgery and is not influenced by vaccinations.

In your case, you mentioned experiencing blurred vision after receiving the AZ vaccine. It is crucial to note that the timing of your symptoms does not imply causation. The development of PCO is generally a gradual process and is not directly triggered by vaccination. The fact that you had a check-up before the vaccine and were informed that everything was fine suggests that the PCO likely developed independently of the vaccination.

As for the treatment of PCO, the standard procedure is a laser treatment called YAG laser capsulotomy. This outpatient procedure involves using a laser to create an opening in the cloudy capsule, allowing light to pass through and restoring clear vision. The procedure is quick, typically taking only a few minutes, and is usually performed under local anesthesia. Most patients experience immediate improvement in vision after the procedure.

Regarding your questions about the number of treatments required and the likelihood of recurrence, YAG laser capsulotomy is generally effective, and most patients only need one treatment. However, in some cases, a small percentage of patients may experience PCO again after several years, necessitating a repeat procedure. While it is not possible to completely prevent PCO, certain factors can influence its development, such as the type of cataract surgery performed and individual healing responses.
To summarize, the development of posterior capsule opacity is a common occurrence following cataract surgery and is not linked to the COVID-19 vaccine. The condition is typically treated effectively with YAG laser capsulotomy, and while recurrence is possible, it is relatively uncommon. Regular follow-up with your ophthalmologist is essential to monitor your eye health and address any concerns promptly. If you have further questions or experience any new symptoms, do not hesitate to reach out to your eye care provider for personalized advice and care.

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