T3b Prostate Cancer: Treatment, Prognosis, and Care - Urology

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Prostate cancer patient


Hello: I am a T3b prostate cancer patient, which has spread to the seminal vesicles, with a Gleason score of 4+3.
I underwent radiation therapy a year ago and am currently receiving hormone therapy, which my doctor said will last for 2 years.
I have just completed 1 year of treatment, and my current PSA level is 0.08.
I would like to ask:
1.
Is there any chance of cure for T3b patients? Even if the probability is very low, if not, what is the average life expectancy?
2.
Can the Gleason score change? If so, how does it change?
3.
Is it advisable to massage the prostate? Will massage improve its health, or could it make things worse?
4.
Could you please comment on whether my current treatment status is acceptable? Thank you very much.

Mr. Chen, 60~69 year old female. Ask Date: 2021/06/28

Dr. Du Shixi reply Urology


Hello: The treatment for prostate cancer, including surgery and radiation therapy, has the potential for cure, but it is important to discuss this with your attending physician.
As for average life expectancy, you can refer to the prognosis section at https://www.canceraway.org.tw/cancerinfo.asp?id=B4202C4F-D7E6-4DF8-B5A3-A23947973BAF.

2.
Will the Gleason score change? If so, how might it change? (If biopsies are performed, since only a small sample is taken, there may be some variability in the results.)
3.
Can the prostate be massaged? Would massage improve its health, or could it make things worse? (There is no need for specific massage; walking can be considered.)
4.
Please comment on whether my current treatment status is okay.
Thank you very much.
Please discuss this with your attending physician.

Reply Date: 2021/06/28

More Info


Understanding T3b Prostate Cancer: Treatment, Prognosis, and Care
Prostate cancer is a significant health concern, particularly in men over the age of 50. The T3b classification indicates that the cancer has spread beyond the prostate gland to nearby structures, such as the seminal vesicles. In your case, with a Gleason score of 4+3, this suggests a moderately aggressive cancer. You have undergone radiation therapy and are currently on hormone therapy, which is a common treatment approach for advanced prostate cancer.

1. Possibility of Cure and Life Expectancy:
T3b prostate cancer is generally considered advanced, and while the chances of a complete cure are lower compared to earlier stages, it is not entirely impossible. The prognosis can vary significantly based on individual factors, including overall health, response to treatment, and specific characteristics of the cancer. With a PSA level of 0.08 after one year of hormone therapy, it suggests that the treatment is effectively controlling the cancer at this stage. However, the average life expectancy for T3b patients can range widely. Some studies indicate that patients with advanced prostate cancer can live for several years, especially with effective management strategies. It is essential to have ongoing discussions with your healthcare provider to understand your specific prognosis better.

2. Gleason Score Changes:
The Gleason score is determined based on the microscopic appearance of cancer cells and can change if new biopsies are performed. If a biopsy is taken from a different area of the prostate or if the cancer progresses, the score may reflect a more aggressive disease. Regular monitoring and biopsies can provide updated information about the cancer's behavior and help guide treatment decisions.

3. Prostate Massage:
Prostate massage is not a standard treatment for prostate cancer and is generally not recommended. While some believe it may help with certain prostate conditions, there is no scientific evidence to support that it can improve cancer outcomes. In fact, it could potentially irritate the prostate or lead to complications. Gentle physical activity, such as walking, is often encouraged to maintain overall health and well-being.

4. Current Treatment Evaluation:
Your current treatment regimen of hormone therapy following radiation therapy appears to be appropriate for managing T3b prostate cancer. The fact that your PSA levels are low is a positive sign, indicating that the hormone therapy is likely effective. However, it is crucial to maintain regular follow-ups with your oncologist to monitor your condition closely. They can adjust your treatment plan based on your response and any side effects you may experience.

In conclusion, while T3b prostate cancer presents challenges, advancements in treatment options and ongoing research provide hope for many patients. It is vital to stay informed, maintain open communication with your healthcare team, and consider supportive care options to enhance your quality of life during treatment. Regular check-ups and monitoring will be key in managing your health moving forward.

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