Vaccination Considerations for Seniors with Chronic Conditions - Cardiology

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Three Highs and Vaccine Administration


Hello, doctor.
A 73-year-old female patient has chronic conditions including E1165 type 2 diabetes with hyperglycemia, E780 pure hypercholesterolemia, J441 chronic obstructive pulmonary disease with (acute) exacerbation, I119 hypertensive heart disease without heart failure, and E782 mixed hyperlipidemia.
She has also experienced symptoms such as R002 palpitations, R42 dizziness and vertigo, R079 chest pain, and R0600 dyspnea and asthma.
Currently, she is taking the following medications: AA42704100 Amlodipine 5 mg, AC470861G0 Metformin 500 mg, AC363491G0 Glimepiride 500 mg, and BC25350100 Rosuvastatin 2 mg.

1.
Which vaccine is more suitable for her, the AstraZeneca (AZ) or Moderna vaccine? Or is there not much difference between them?
2.
I came across an article stating, "If blood sugar is above 400, the risk of complications when getting vaccinated is quite high." It seems that vaccination sites only check blood pressure and temperature before administering the vaccine, without checking blood sugar levels.
This raises some concerns.
Is it true that patients with diabetes should avoid vaccination when their blood sugar is high?
3.
Should chronic disease medications be paused before and after vaccination? Thank you.

San, 70~79 year old female. Ask Date: 2021/06/28

Dr. Li Han reply Cardiology


Hello, regarding your concerns about COVID-19 vaccination, the chronic comorbidities you mentioned are not contraindications for receiving the COVID-19 vaccine (including AstraZeneca).
In fact, age and these comorbidities may increase your risk of contracting the virus during the pandemic.
In summary, the benefits of vaccination far outweigh the potential side effects, whether it is AstraZeneca or Moderna.
The Ministry of Health and Welfare Changhua Hospital cares about your well-being.

Reply Date: 2021/06/28

More Info


Vaccination is a crucial aspect of healthcare, especially for seniors with chronic conditions. In the case of a 73-year-old female patient with multiple chronic diseases such as type 2 diabetes, hyperlipidemia, chronic obstructive pulmonary disease (COPD), and hypertension, careful consideration must be given to her vaccination options.

1. Vaccine Choice: AZ vs. Moderna
Both the AstraZeneca (AZ) and Moderna vaccines are effective against COVID-19, but they have different profiles. The Moderna vaccine, an mRNA vaccine, has shown a higher efficacy rate in clinical trials compared to the AZ vaccine, which is a viral vector vaccine. For seniors, particularly those with chronic conditions, the mRNA vaccines like Moderna may provide a stronger immune response. However, the choice between the two vaccines should also consider individual health status, potential side effects, and availability. Given her chronic conditions, it is advisable to consult with her healthcare provider to determine the most suitable vaccine based on her medical history and current health status.

2. High Blood Sugar and Vaccination
The concern regarding high blood sugar levels, particularly above 400 mg/dL, is valid. Elevated blood sugar can lead to complications such as infections and delayed wound healing, which can increase the risk of adverse reactions to vaccinations. While there is no strict contraindication for vaccinating individuals with high blood sugar, it is generally recommended to manage blood glucose levels as much as possible before vaccination. If her blood sugar is significantly elevated, it may be prudent to delay vaccination until it is better controlled. However, this decision should be made in consultation with her healthcare provider, who can assess her overall health and the urgency of vaccination.

3. Medication Management Around Vaccination
Regarding the management of chronic medications around the time of vaccination, it is typically not necessary to pause medications unless specifically advised by a healthcare provider. For instance, medications for diabetes, hypertension, and hyperlipidemia should generally be continued to maintain stable health conditions. However, it is essential to discuss any concerns with her healthcare provider, as they may have specific recommendations based on her medications and overall health status.

In summary, for a senior with multiple chronic conditions, the choice of vaccine should be made in consultation with a healthcare provider, considering the individual's health status and the potential risks associated with high blood sugar levels. It is crucial to manage chronic conditions effectively and continue necessary medications around the time of vaccination. Regular monitoring and communication with healthcare professionals will ensure that the patient receives the best possible care and protection against COVID-19.

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