Painless Hematuria: Possible Causes and Concerns - Urology

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Inquiry about painless hematuria?


Hello, doctor.
I have searched through the question bank and found no similar issues, so I am inquiring.
I have been living abroad for four months, and two weeks ago, I noticed blood on the toilet paper after urinating, but there was no blood in the toilet.
It doesn't happen every time I urinate; sometimes, it occurs more after having a bowel movement.
I am very certain it is not menstruation (as I am postmenopausal) and it is not hemorrhoidal bleeding.
Originally, I had not seen blood for two days, but after drinking a lot of water and holding my urine for about 30 minutes for an ultrasound, I noticed blood again after urinating.
The blood is a light red color, and my urine is very clear and not cloudy.
I drink water regularly and do not hold my urine.
There is no pain while urinating, no back pain, no fever, and no swelling; I feel completely fine.
Years ago, I had urinary tract infections and kidney inflammation due to holding my urine, but those were accompanied by significant pain, which I do not have this time.
I have seen a doctor, and both urinalysis and ultrasound of the urinary system and kidneys showed no abnormalities.
What other possible issues could there be?

Ms. Li, 40~49 year old female. Ask Date: 2021/07/02

Dr. Du Shixi reply Urology


Hello: Based on your description, the urine in the toilet appears to be blood-free, but since there is blood on the toilet paper, it is still advisable to have both gynecological and rectal examinations confirmed by a physician.
If there is blood in the toilet, further examinations of the bladder and ureters should be conducted, especially after a kidney ultrasound.
Wishing you good health.

Reply Date: 2021/07/02

More Info


Painless hematuria, or the presence of blood in the urine without accompanying pain, can be concerning and may arise from various underlying causes. Given your situation, where you have experienced intermittent blood in your urine without any other symptoms such as pain, fever, or swelling, it is essential to consider several potential explanations.

Firstly, it is important to note that painless hematuria can sometimes be benign, particularly if it is transient and not accompanied by other symptoms. However, it is crucial to rule out any serious conditions. Here are some possible causes of painless hematuria:
1. Urinary Tract Infections (UTIs): While UTIs typically present with symptoms like burning during urination or frequent urges to urinate, some individuals may experience hematuria without significant discomfort. However, your negative urine tests make this less likely.

2. Kidney Stones: Stones can cause bleeding in the urinary tract, but they often present with pain. In some cases, small stones may pass without causing significant discomfort.

3. Bladder or Kidney Tumors: Both benign and malignant tumors can cause blood in the urine. This is particularly concerning in individuals over 40, and it is essential to have this ruled out through imaging studies and possibly cystoscopy.

4. Glomerular Disease: Conditions affecting the glomeruli in the kidneys can lead to hematuria. These may not always present with pain but can be associated with other symptoms like proteinuria or changes in kidney function.

5. Vascular Issues: Conditions such as renal vein thrombosis or other vascular abnormalities can lead to bleeding in the urinary tract without pain.

6. Medications: Certain medications, particularly anticoagulants or nonsteroidal anti-inflammatory drugs (NSAIDs), can lead to hematuria as a side effect.

7. Exercise-Induced Hematuria: Strenuous exercise can sometimes lead to temporary hematuria, especially in runners. This is usually benign and resolves with rest.

8. Trauma: Any recent trauma to the abdomen or pelvis, even if minor, can lead to bleeding in the urinary tract.

Given that your ultrasound and urine tests have returned normal, it is reassuring, but it does not completely rule out all potential causes. If the hematuria persists or worsens, further evaluation may be warranted. This could include:
- Cystoscopy: A procedure that allows direct visualization of the bladder and urethra, which can help identify any lesions or abnormalities.

- CT Urogram: A specialized imaging study that provides detailed images of the urinary tract and can help identify stones, tumors, or other abnormalities.

- Urine Cytology: This test examines urine for abnormal cells that may indicate cancer.

It is also worth considering lifestyle factors that may contribute to hematuria, such as dehydration or excessive physical activity. Maintaining adequate hydration is crucial, especially if you are in a warmer climate or engaging in physical activities.

In conclusion, while painless hematuria can sometimes be benign, it is essential to remain vigilant and consult with a healthcare provider if symptoms persist or if you have any new concerns. Regular follow-ups and monitoring are advisable to ensure that any underlying issues are addressed promptly. If you have any further questions or if your symptoms change, do not hesitate to seek medical advice.

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