Should Patients with Congenital Hypothyroidism Get the AZ Vaccine? - Internal Medicine

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It is recommended to administer vaccines for individuals with congenital hypothyroidism?


Hello, doctor.
I have congenital hypothyroidism and have been on medication for control.
My blood tests have consistently shown normal results.
Aside from gastritis and slightly elevated body fat, I do not have any other symptoms such as hypertension, hyperglycemia, or hyperlipidemia.
I previously saw a case of a similar patient who experienced shock after receiving the AZ vaccine.
I would like to know if it is still recommended for me to receive the AZ vaccine.
Thank you.

J, 20~29 year old female. Ask Date: 2021/07/15

Dr. Lin Jianliang reply Internal Medicine


Hello, online user: For patients with well-controlled hypothyroidism, if there are no contraindications or precautions regarding the administration of the AZ vaccine, it is recommended that they receive the vaccine.

Reply Date: 2021/07/15

More Info


When considering vaccination with the AstraZeneca (AZ) vaccine for patients with congenital hypothyroidism, it is essential to evaluate both the underlying condition and the potential risks associated with the vaccine. Congenital hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormones from birth, which can lead to various health issues if not managed properly. However, with appropriate medication and regular monitoring, individuals with this condition can lead healthy lives.

Based on current medical guidelines and research, patients with well-managed congenital hypothyroidism are generally considered safe candidates for vaccination, including the AZ vaccine. The key factors to consider include:
1. Stability of the Condition: If your congenital hypothyroidism is well-controlled with medication and regular blood tests show normal thyroid hormone levels, this indicates that your condition is stable. Stability is crucial because it suggests that your body is functioning well and is less likely to have an adverse reaction to the vaccine.

2. Potential Allergic Reactions: Concerns about severe allergic reactions, such as anaphylaxis, have been raised regarding COVID-19 vaccines. However, these reactions are rare. If you have a history of severe allergies or anaphylaxis to other vaccines or injectable medications, it is essential to discuss this with your healthcare provider. They may recommend a pre-vaccination assessment or observation period post-vaccination.

3. Monitoring Post-Vaccination: After receiving the AZ vaccine, it is advisable to remain at the vaccination site for at least 15-30 minutes for monitoring. This is a standard practice to ensure that any immediate allergic reactions can be promptly addressed.

4. Consultation with Healthcare Providers: Given your history of gastric inflammation and elevated body fat, it is also wise to consult with your healthcare provider or an endocrinologist. They can provide personalized advice based on your overall health status and any other medications you may be taking.

5. Risk vs. Benefit Analysis: The benefits of vaccination against COVID-19, particularly in the context of the ongoing pandemic, generally outweigh the risks for most individuals, including those with underlying health conditions. Vaccination can help protect you from severe illness, hospitalization, and complications associated with COVID-19.

In conclusion, if your congenital hypothyroidism is well-managed and you do not have a history of severe allergic reactions to vaccines, it is likely safe for you to receive the AZ vaccine. However, always consult with your healthcare provider to discuss your specific health circumstances and any concerns you may have. They can provide the most accurate and personalized recommendations based on your medical history and current health status.

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