COVID-19 Vaccine Injection Concerns: Tetanus and Allergy Considerations - Internal Medicine

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Issues related to COVID-19 vaccination?


Hello, doctor.
I am inquiring on behalf of a friend regarding COVID-19 vaccination questions.
The questions are as follows: 1.
If they recently received a tetanus shot (about 2 weeks ago), is it safe to receive the vaccine? 2.
They had an allergic reaction to a contrast agent due to kidney issues (currently around 37 years old).
Which type of vaccine should they choose? Thank you for your clarification.

Gavin, 40~49 year old female. Ask Date: 2021/07/16

Dr. Hong Yuanbin reply Internal Medicine


Hello,
1.
There are currently no relevant international recommendations regarding this matter; however, expert consensus generally suggests that different types of vaccines should be administered at least one month apart for optimal results.

2.
It is true that the Moderna vaccine formulation contains TROMETAMOL, which has been reported to be associated with contrast agents in the past.
However, neither Taiwan nor the United States currently lists it as a contraindication.
Additionally, the ionic contrast agents used previously differ from the mainstream non-ionic contrast agents today, so it is not considered an absolute contraindication.
If you have concerns, you may consider receiving a "non"-Moderna COVID-19 vaccine.
Thank you for your inquiry.

Reply Date: 2021/07/16

More Info


When considering the administration of the COVID-19 vaccine, especially in the context of recent medical history such as receiving a tetanus shot or having a history of allergic reactions, it is essential to approach the situation with caution and informed decision-making.

1. Recent Tetanus Shot: If you have received a tetanus shot within the last two weeks, it is generally safe to receive the COVID-19 vaccine. The Centers for Disease Control and Prevention (CDC) and other health authorities recommend that individuals can receive the COVID-19 vaccine regardless of recent vaccinations, including tetanus. However, it is advisable to wait at least 14 days between receiving different vaccines to ensure that any potential side effects can be properly monitored and attributed to the correct vaccine. This is particularly important if you experience any adverse reactions, as it helps healthcare providers determine the cause.

2. History of Allergic Reactions: Given your history of allergic reactions to a contrast agent used in kidney imaging, it is crucial to choose a COVID-19 vaccine that aligns with your medical history. Both mRNA vaccines (Pfizer-BioNTech and Moderna) and viral vector vaccines (like Johnson & Johnson and AstraZeneca) have been shown to be effective against COVID-19. However, if you have a known allergy to components of a specific vaccine, it is essential to avoid that vaccine. For instance, if you have a history of severe allergic reactions (anaphylaxis) to polyethylene glycol (PEG), which is found in some mRNA vaccines, you should consult with your healthcare provider about the best option for you.

In general, individuals with a history of allergies are advised to consult with their healthcare provider before vaccination. They may recommend monitoring you for a longer period post-vaccination (30 minutes instead of the standard 15 minutes) to ensure that any allergic reactions can be promptly addressed.

Additional Considerations:
- Consultation with Healthcare Provider: Before proceeding with vaccination, it is wise to have a detailed discussion with your healthcare provider. They can assess your overall health, review your medical history, and determine the most appropriate vaccine for you.

- Monitoring for Side Effects: After receiving the vaccine, be vigilant for any side effects. Common side effects include pain at the injection site, fatigue, headache, muscle pain, chills, fever, and nausea. These are generally mild and resolve within a few days. However, if you experience severe allergic reactions, such as difficulty breathing, swelling of the face or throat, or a rapid heartbeat, seek immediate medical attention.

- Vaccination Timing: If you have any acute illness or are experiencing significant health issues, it is advisable to postpone vaccination until you are fully recovered. The CDC recommends waiting until you are symptom-free and have recovered from any acute illness before receiving the vaccine.

In conclusion, receiving the COVID-19 vaccine after a recent tetanus shot is generally safe, and your history of allergic reactions should be carefully considered when choosing which vaccine to receive. Always consult your healthcare provider for personalized advice and to ensure that you are making the best decision for your health. Vaccination remains a critical tool in controlling the spread of COVID-19 and protecting public health.

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