Metastatic Colon Cancer Treatment and Emotional Support - Oncology

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Cancer treatment


My husband has metastatic colorectal cancer and has undergone resection of the malignant tumor at Shuanghe Hospital.
He had his third chemotherapy session on July 21, with a total of five sessions planned.
A CT scan is scheduled for mid-August to assess the treatment's effectiveness.
The treatment regimen prescribed by the doctor includes 5-FU, Leucovorin, and a second dose of targeted therapy with Cetuximab.
The last CT scan was performed on May 11 at National Taiwan University Hospital, where I noticed shadows measuring 1.98 cm and 2.2 cm, as well as white calcifications scattered throughout the liver resembling small dots.
I would like to ask the doctor the following questions:
First: Why is a CT scan needed to evaluate the treatment's effectiveness after only five chemotherapy sessions? Does the doctor believe that the liver tumors are small enough that the medication can bring the condition under control?
Second: Will the white calcifications in the liver disappear with the chemotherapy drugs and targeted therapy mentioned above?
Third: Are the white calcifications indicative of cancerous tumors? Why do they appear as white calcifications?
Fourth: My husband has cancer, but I find myself feeling depressed and worried every day due to the uncertainty of the medical treatment and his condition.
I cannot pretend that everything is fine.
How can I adjust my mood?

Hui Ting, 30~39 year old female. Ask Date: 2021/07/16

Dr. Hu Ziren reply Oncology


It is recommended to have a detailed discussion with the attending physician; if necessary, you can request a consultation with an oncology psychologist, social worker, or other holistic support services!

Reply Date: 2021/07/16

More Info


Understanding metastatic colon cancer treatment and the emotional challenges that accompany it is crucial for both patients and their families. Your husband’s treatment plan, which includes chemotherapy and targeted therapy, is designed to manage the disease and improve his quality of life. Let’s address your questions one by one.

1. Why is a CT scan scheduled after five chemotherapy sessions?
The decision to perform a CT scan after five cycles of chemotherapy is standard practice in oncology. This imaging helps assess the effectiveness of the treatment. In your husband’s case, the oncologist likely believes that the tumors in the liver may be small enough to respond positively to the chemotherapy regimen he is undergoing. The goal of chemotherapy is not only to shrink tumors but also to control disease progression. By evaluating the treatment response through imaging, the medical team can make informed decisions about continuing, adjusting, or changing the treatment plan based on the results.

2. Will the chemotherapy and targeted therapy eliminate the white calcified spots in the liver?
The white calcified spots you mentioned could represent a variety of conditions, including benign lesions or areas of previous tumor activity that have calcified. Chemotherapy and targeted therapies can reduce the size of tumors and potentially eliminate active cancer cells, but they may not necessarily cause calcified lesions to disappear. The calcification itself is often a sign that the body has responded to the tumor in some way, such as through healing or scarring. It’s essential to discuss these findings with your husband’s oncologist, who can provide more specific insights based on his imaging results.

3. Are the white calcified spots cancer cells? Why are they calcified?
Calcified spots in the liver can be due to several reasons, including previous infections, benign tumors, or areas where cancer cells have died and left behind calcified tissue. In the context of metastatic cancer, calcification can occur when tumor cells die due to treatment, leading to a process called necrosis, which can result in calcified lesions. However, not all calcified spots indicate active cancer; they may simply be remnants of past lesions. Again, a thorough evaluation by the oncologist is necessary to determine the nature of these calcifications.

4. How can I manage my emotional well-being while supporting my husband?
Caring for a loved one with cancer can be emotionally taxing. It’s natural to feel overwhelmed, anxious, or even depressed. Here are some strategies to help you cope:
- Seek Support: Consider joining a support group for caregivers or individuals affected by cancer. Sharing experiences with others who understand can be incredibly validating and comforting.

- Communicate Openly: Talk to your husband about your feelings and encourage him to share his as well. Open communication can strengthen your bond and help both of you feel less isolated in your experiences.

- Practice Self-Care: Make time for activities that bring you joy and relaxation. Whether it’s reading, exercising, or spending time with friends, self-care is essential for maintaining your mental health.

- Consider Professional Help: If feelings of anxiety or depression persist, it may be beneficial to speak with a mental health professional. They can provide coping strategies tailored to your situation.

- Stay Informed: Understanding your husband’s condition and treatment can help alleviate some fears. Don’t hesitate to ask questions during medical appointments or seek clarification on treatment plans.

- Focus on the Present: While it’s easy to worry about the future, try to focus on the present moment. Engage in activities together that you both enjoy, creating positive memories amidst the challenges.

In conclusion, navigating metastatic colon cancer treatment is a complex journey that requires both medical and emotional support. By staying informed, communicating openly, and taking care of your emotional health, you can better support your husband while also caring for yourself. Remember, you are not alone in this journey, and seeking help is a sign of strength.

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