Hormonal Effects on Axillary Lumps Before Menstruation - Breast and Thyroid

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Before menstruation, there is always swelling and pain in the right armpit, and a lump can be felt?


Hello, Doctor: I would like to inquire whether the swelling of the axillary lymph nodes is related to the menstrual cycle.
I have accessory breast tissue on my right side (which is larger than the left), and I experience breast and right axillary swelling and pain after ovulation (the left side does not have this issue).
I can feel a lump in my right axilla, but it usually reduces in size and becomes almost undetectable after my menstrual period starts, and the pain subsides as well.
In 2012, I discovered two fibroadenomas measuring 0.6 cm and 0.8 cm on the left side, which were confirmed to be benign through fine needle aspiration.
Since then, I have been regularly monitored with breast ultrasounds every year.
It was about three years after the discovery of the left fibroadenomas that I began experiencing swelling and pain in my right axilla.
When I consulted my doctor, they did not provide specific comments, only suggesting to continue regular ultrasound follow-ups.
I have been following this routine for about 5 to 6 years (with no significant changes in the size of the fibroadenomas).
Therefore, I would like to ask if the issues in my right axilla could possibly be related to hormonal changes during the menstrual cycle or the presence of accessory breast tissue, which might be causing the swelling, pain, or even the palpable lump?

Xiao Yang, 20~29 year old female. Ask Date: 2021/07/19

Dr. Yuan Tianmin reply Breast and Thyroid


Actually, the menstrual cycle can be related to axillary accessory breast tissue, so I believe your condition is more associated with the accessory breast tissue.

Reply Date: 2021/07/19

More Info


The relationship between hormonal fluctuations during the menstrual cycle and axillary (underarm) lumps or lymphadenopathy is a topic of interest for many women. Your observations regarding the swelling and tenderness in your right axilla, particularly in relation to your menstrual cycle, are indeed valid and can be explained through hormonal influences.

During the menstrual cycle, particularly in the luteal phase (which occurs after ovulation and before menstruation), there is a significant increase in the levels of hormones such as progesterone and estrogen. These hormones can lead to changes in breast and surrounding tissue, including the lymph nodes in the axillary region. The swelling and tenderness you experience in your right axilla and breast may be attributed to these hormonal changes, especially since you have noted that the symptoms subside with the onset of menstruation.

The presence of accessory breast tissue (supernumerary breast tissue) on the right side may also contribute to the sensations you are experiencing. This tissue can be more sensitive to hormonal changes, leading to increased swelling and tenderness during certain phases of your menstrual cycle. The fact that you have a history of fibrocystic changes, such as the benign fibroadenomas you mentioned, can also play a role in how your breast and surrounding tissues respond to hormonal fluctuations.

It is important to note that while hormonal changes can cause temporary swelling and tenderness in the axillary region, persistent lumps or changes should always be evaluated by a healthcare professional. Regular monitoring through ultrasound, as you have been doing, is a prudent approach, especially since you have a history of benign breast conditions. The fact that your fibroadenomas have remained stable in size over the years is reassuring, but any new or changing symptoms should be discussed with your doctor.

In summary, the swelling and tenderness in your right axilla likely correlate with hormonal changes associated with your menstrual cycle, compounded by the presence of accessory breast tissue. It is essential to maintain regular follow-ups and imaging as recommended by your healthcare provider to ensure that any changes are monitored appropriately. If you notice any significant changes in the lumps or if new symptoms arise, do not hesitate to seek further evaluation. Your health and peace of mind are paramount, and understanding the interplay between hormones and breast tissue can help you navigate these concerns effectively.

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