Penile Folliculitis: Duration and HSV Testing Insights - Urology

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Pilonidal cyst issues?


Hello Doctor: In early May, I developed a bump on my penis that looked like a pimple (it had a whitehead and I was able to squeeze out some pus).
I consulted two doctors at that time, and they both diagnosed it as folliculitis.
However, it has not completely resolved even after two months.
Q1: I would like to ask, is it possible for folliculitis to persist for more than two months without healing? (I have been applying medication and I also tend to have acne.) Additionally, 41 days after the bump appeared, I had a blood test for HSV2 IgG, which came back negative (while HSV1 IgG was positive).
Q2: I would like to know if this report is of any significance.
Is there a possibility of a false negative result for the HSV2 test? (I have not engaged in any sexual activity or contact since the bump appeared.) Thank you for your response, Doctor.
I apologize for the trouble.

H, 20~29 year old female. Ask Date: 2021/07/25

Dr. Du Shixi reply Urology


Hello:
Q1: I would like to ask the doctor if folliculitis can persist for more than two months without resolving? (I have been applying medication consistently, and I also tend to have acne.) -- It is possible.
Additionally, after the appearance of that pimple-like lesion, I had a blood test for HSV-2 IgG 41 days later, and the result was negative.
(HSV-1 IgG was positive.)
Q2: I would like to ask the doctor if this report has any reference value? Is there a possibility of a false negative for the HSV-2 test? (There has been no sexual activity or contact since the lesion appeared.) -- Yes, false negatives are certainly possible; any test can yield false negatives.
However, folliculitis is unlikely to be related to HSV.
Wishing you good health.

Reply Date: 2021/07/25

More Info


Understanding penile folliculitis and its relationship with HSV testing can be quite complex, especially when considering the nuances of skin conditions and viral infections. Let's break down your questions and provide a comprehensive understanding.

Q1: Duration of Folliculitis
Folliculitis, which is the inflammation of hair follicles, can indeed persist for an extended period, sometimes lasting several weeks to months. The duration of folliculitis can be influenced by several factors, including the underlying cause, the individual's skin type, hygiene practices, and the effectiveness of the treatment being applied. In your case, if you have been consistently applying medication as prescribed and the condition has not fully resolved after two months, it may warrant further evaluation.

Persistent folliculitis can sometimes be due to bacterial infections, fungal infections, or even irritation from shaving or other grooming practices. If the lesion has not improved or has worsened, it may be beneficial to consult a dermatologist for a more thorough examination. They might consider alternative diagnoses, such as a different type of infection or a skin condition that mimics folliculitis.

Q2: HSV Testing Insights
Regarding your HSV testing, it’s important to understand the implications of your results. You mentioned that your HSV2 IgG test was negative, while your HSV1 IgG was positive. This indicates that you have been exposed to HSV1, which is commonly associated with oral herpes but can also cause genital infections. The negative HSV2 IgG result suggests that you have not been exposed to HSV2, which is typically associated with genital herpes.

However, it is crucial to recognize that no test is perfect. The possibility of a false negative result exists, particularly if the test was conducted shortly after exposure to the virus. The window period for HSV2 IgG testing is generally around 4 to 12 weeks post-exposure for accurate results. Since you mentioned that the test was done 41 days after the appearance of the lesion, it falls within this window, and there is a chance that the test may not have detected an infection if it was recent.

Given that you have not engaged in any sexual activity since the lesion appeared, the likelihood of contracting HSV2 from another source during that time is low. However, if you have concerns about potential exposure or if symptoms persist, it may be advisable to retest after a few weeks or consult with a healthcare provider for further evaluation.

In summary, while folliculitis can last for an extended period, persistent symptoms should be re-evaluated by a healthcare professional. Your HSV testing indicates no current HSV2 infection, but the timing of the test should be considered when interpreting the results. If you have further concerns or if the lesion does not resolve, seeking a specialist's opinion would be a prudent step. Always prioritize open communication with your healthcare provider to ensure that you receive the most accurate diagnosis and appropriate treatment.

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