Can I Rule Out STDs After Negative Tests and No Recent Sexual Activity? - Urology

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Exclusion of sexually transmitted infections (STIs)


Hello Doctor: Two years ago, I had a one-night stand with a woman, which involved unprotected oral sex and protected vaginal intercourse.
Although I have not experienced any symptoms such as rashes, I recently went to a medical laboratory for testing due to concerns about sexually transmitted infections (STIs).
The results for syphilis antibodies ("STS RPR and STS TPHA") and HIV screening ("HIV ab.") were both negative.
Since that sexual encounter two years ago, I have not engaged in any sexual activity.
Can I rule out the possibility of having contracted an STI? Am I being overly worried? Thank you.

Niming, 20~29 year old female. Ask Date: 2021/07/26

Dr. Du Shixi reply Urology


Hello: The tests conducted by the medical laboratory should also be reliable.
Based on your description, there should be no infection of syphilis or HIV.
Wishing you good health.

Reply Date: 2021/07/26

More Info


Based on your situation, it appears that you are understandably concerned about the possibility of having contracted a sexually transmitted disease (STD) after engaging in unprotected sexual activities two years ago. You have since undergone testing for syphilis and HIV, both of which returned negative results. Additionally, you have not engaged in any sexual activity since that time.
To address your question: Yes, based on the information provided, it is reasonable to conclude that you can rule out the possibility of having contracted an STD from the encounter you described. The negative results from your tests for syphilis (STS RPR and STS TPHA) and HIV (HIV Ab) are strong indicators that you have not been infected with these particular STDs.
It's important to note that the window period for testing varies by STD. For HIV, most tests can reliably detect the virus within 2 to 4 weeks after exposure, with some tests being able to detect it as early as 10 days post-exposure. However, the most reliable results are typically obtained at 3 months after exposure. In your case, since you tested negative well beyond this window period, it is highly unlikely that you are infected with HIV. Similarly, syphilis tests are also quite accurate after a few weeks post-exposure, and given your negative results, it is unlikely that you have syphilis.

Regarding your concerns about whether you might be overthinking the situation, it is not uncommon for individuals to experience anxiety about potential STDs, especially after high-risk encounters. This anxiety can sometimes lead to obsessive thoughts about health and safety. It is essential to recognize that while it is wise to be cautious and get tested, it is also important to trust the results of your tests and the time that has passed since your last sexual encounter.

If you continue to experience anxiety about this issue, consider speaking with a healthcare professional or a counselor who specializes in sexual health. They can provide you with further reassurance and help you manage any lingering fears or concerns.
In summary, based on your negative test results and the time elapsed since your last sexual encounter, you can confidently rule out the possibility of having contracted STDs from that encounter. However, if you have any new symptoms or concerns in the future, it is always best to consult with a healthcare provider for further evaluation and testing. Remember, maintaining open communication with healthcare professionals can help alleviate anxiety and ensure your sexual health is monitored appropriately.

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