Can Patients with Kikuchi Disease Safely Receive the COVID-19 Vaccine?

Can individuals with Kikuchi disease receive the COVID-19 vaccine?

In 2019, I discovered a sudden round lump in my neck.
The doctor recommended immediate surgery for removal and examination, which resulted in a diagnosis of Kikuchi disease.
The doctor mentioned that the cause is currently unclear and there are no specific precautions to take, suggesting it may be related to autoimmune dysregulation where the body attacks itself.
Online information indicates that it may resolve over time, but I am unsure if it can fully recover.
Over the past two years, I have consistently experienced mild dryness and pain in my throat, similar to the onset of a cold.
I would like to know where I can get an oral bacterial culture test done.
Recently, I read that individuals with autoimmune issues should consult a doctor regarding vaccinations.
I am concerned whether receiving the COVID-19 vaccine could trigger other issues related to Kikuchi disease.

Ms. Tseng, 20~29 year old female. Ask Date: 2021/07/28

Dr. Zheng Jueyi reply Otolaryngology

Hello, general hospitals can perform oral bacterial cultures, but the oral cavity naturally contains many normal flora.
If you need to check, you may consult a rheumatologist.
The cause of Kikuchi disease is still unclear, and if there are currently no acute symptoms, there should be no significant contraindications.
If you have concerns, it is also advisable to schedule an appointment with a rheumatologist.
Wishing you peace and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2021/07/28

More Info

Kikuchi disease, also known as Kikuchi-Fujimoto disease, is a rare, benign condition characterized by lymphadenopathy (swollen lymph nodes) and fever, often associated with self-limiting lymphadenitis. It is believed to be related to autoimmune processes, although the exact cause remains unclear. Patients with Kikuchi disease typically experience a good prognosis, with most recovering completely within a few months without any specific treatment. However, some may experience lingering symptoms, such as mild throat discomfort, as you've described.

When it comes to vaccination, particularly the COVID-19 vaccine, individuals with autoimmune conditions or those who have experienced autoimmune diseases like Kikuchi disease often have concerns about vaccine safety and efficacy. Generally, the COVID-19 vaccines authorized for use have been shown to be safe and effective for most individuals, including those with a history of autoimmune diseases. However, it is crucial to consult with a healthcare provider before proceeding with vaccination.

Here are some key points to consider regarding the COVID-19 vaccine and Kikuchi disease:
1. Immune Response: The immune response to vaccines can be different in individuals with autoimmune conditions. However, Kikuchi disease is typically self-limiting and does not usually compromise the immune system significantly. Therefore, patients with a history of Kikuchi disease may still mount an adequate immune response to the vaccine.

2. Consultation with Healthcare Provider: It is essential to discuss your specific medical history and any ongoing symptoms with your healthcare provider. They can assess your overall health, the status of your Kikuchi disease, and any other factors that may influence your vaccination decision.

3. Monitoring for Side Effects: After receiving the COVID-19 vaccine, it is important to monitor for any side effects. Common side effects include soreness at the injection site, fatigue, headache, and mild fever. If you experience any unusual or severe symptoms, you should seek medical attention.

4. Oral Bacterial Culture: If you are concerned about your throat discomfort and want to investigate further, you can consult an ear, nose, and throat (ENT) specialist or your primary care physician. They can recommend appropriate tests, including an oral bacterial culture, to identify any underlying infections or issues.

5. Vaccination Timing: If you are currently experiencing symptoms or have recently had a flare-up of Kikuchi disease, it may be advisable to wait until you are feeling better before getting vaccinated. Your healthcare provider can help determine the best timing for your vaccination.

In conclusion, while Kikuchi disease does not typically pose a significant risk regarding COVID-19 vaccination, individual circumstances can vary. It is crucial to have an open dialogue with your healthcare provider to make an informed decision that considers your health history and current condition. Vaccination remains one of the most effective strategies to protect against severe illness from COVID-19, and your healthcare provider can help ensure that you are safely able to receive the vaccine.

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