Managing GERD: Timing and Effects of Your Medication Explained - Gastroenterology and Hepatology

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Gastroesophageal reflux disease (GERD)


Hello, Vice Dean Chen: I am Miss Song.
I have gastroesophageal reflux disease (GERD) and have undergone an endoscopy at Changhua Christian Hospital Yunlin Branch, which showed normal results.
However, Dr.
Yang Jia-wei prescribed me Nexium (esomeprazole) to treat my GERD symptoms.
I would like to ask whether this medication should be taken before breakfast or before dinner, and how long I should wait after taking it before eating.
I also want to know why I start feeling hungry before noon or dinner after taking this medication, as this has caused me to gain weight.
Thank you for your response, Vice Dean Chen.

Miss Song, 30~39 year old female. Ask Date: 2021/08/01

Dr. Chen Shidian reply Gastroenterology and Hepatology


Nateglinide should be taken on an empty stomach, once a day, either in the morning or evening.
Some patients may experience hunger; it may be helpful to try taking it before bedtime or when switching medications.

Reply Date: 2021/08/01

More Info


Dear Ms. Song,
Thank you for your inquiry regarding the management of gastroesophageal reflux disease (GERD) and the timing of your medication, specifically the use of the drug "Nexium" (Esomeprazole). It's great to hear that you've had a thorough evaluation with an endoscopy, which is a crucial step in diagnosing GERD and ruling out other potential issues.

Timing of Medication:
Nexium is a proton pump inhibitor (PPI) that works by reducing the amount of acid your stomach produces. For optimal effectiveness, it is generally recommended to take Nexium at least 30 to 60 minutes before a meal, preferably in the morning. This timing allows the medication to be absorbed effectively and to inhibit acid production before you eat, which can help minimize GERD symptoms.

If you are taking Nexium before breakfast, you should wait at least 30 minutes after taking the medication before eating. If you are taking it before dinner, the same rule applies. This timing is essential because it allows the medication to work effectively in reducing stomach acid during your meal, which can help prevent reflux symptoms.

Feeling Hungry:
Regarding your experience of feeling hungry shortly after taking the medication, this can be attributed to several factors. PPIs like Nexium can sometimes lead to changes in gastric motility and may affect how quickly food moves through your stomach. Additionally, if you are taking the medication on an empty stomach, it may lead to a sensation of hunger as your stomach is prepared for food but not receiving it immediately.

It's also worth noting that some individuals may experience an increase in appetite or changes in dietary habits when they start taking medications for GERD, especially if they previously avoided certain foods due to discomfort. If you find that your hunger is leading to increased caloric intake and subsequent weight gain, it may be beneficial to monitor your diet closely and consider discussing this with your healthcare provider.

Weight Management:
Weight gain can be a concern for many individuals taking medications for GERD, particularly if they are experiencing increased appetite. It's essential to maintain a balanced diet and consider portion control to manage your weight effectively. Incorporating regular physical activity can also help mitigate weight gain.

If you continue to experience significant hunger or if your weight gain becomes a concern, I recommend discussing this with your physician. They may suggest dietary modifications or adjustments to your medication regimen to better suit your needs.

Conclusion:
In summary, take Nexium 30 to 60 minutes before meals for optimal effectiveness, and be mindful of your hunger cues and dietary habits. If you have further concerns about your GERD management or weight gain, please do not hesitate to reach out to your healthcare provider for personalized advice.

Wishing you good health and relief from your symptoms.

Best regards,
Doctor Q&A Teams

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