Nighttime Headaches: Causes and Concerns After Vaccination - Neurology

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The headache has persisted for several days and is causing nighttime awakenings?


I received the vaccine on July 23, 2021, and started experiencing side effects the next day, including headaches and muscle and joint pain.
However, aside from headaches and dizziness, I returned to normal by the third day.
On the fourth day, at around 5 AM, I suddenly experienced severe pain in my head, which has persisted for nearly a week now.
The muscle area near my right temple has been in a constant state of tight pain throughout the day, although it is bearable.
I have consulted a doctor who indicated that my symptoms do not resemble those typically associated with post-vaccination thrombosis.
The most distressing part is that I wake up in pain during the night, making it difficult to fall back asleep, and I feel fatigued throughout the day.

Doctor, does waking up in pain at night necessarily indicate a neurological disorder? Is it possible that migraines or tension-type headaches could also cause symptoms of waking up in pain at night? Aside from waking up in pain, I have not experienced any other neurological symptoms, such as weakness in the limbs, slurred speech, unilateral paralysis, or blurred vision.

Niming, 40~49 year old female. Ask Date: 2021/08/02

Dr. Jiang Junyi reply Neurology


Hello, sir: May I ask if you received the AZ vaccine? The adverse reaction of thrombosis associated with the AZ vaccine is currently referred to as VITT (Vaccine-induced immune thrombotic thrombocytopenia).
The incidence rate is approximately 1 in 10,000 in Europe.
It typically occurs between 4 to 28 days after vaccination.
Please be vigilant for symptoms such as: swelling in the lower limbs, shortness of breath, headache accompanied by blurred vision, and persistent abdominal pain lasting more than 24 hours.

Clinically, if cerebral venous sinus thrombosis is suspected, MRI is required for diagnosis.
For abdominal or pulmonary embolism, a CT scan with contrast is necessary, while deep vein thrombosis in the lower limbs can be assessed using vascular ultrasound.
Blood tests should include PT, aPTT, D-dimer (elevated more than four times), and fibrinogen (severely decreased).
Nighttime headaches may warrant consideration of sleep apnea or cluster headaches within the category of vascular headaches.
If you continue to experience headaches, it is advisable to seek assistance from a neurologist for diagnosis.

Please ensure to practice self-protection, maintain cleanliness and disinfection, and adhere to new preventive measures before and after seeking medical care.
Thank you for your inquiry, and feel free to discuss any related questions! Wishing you good health, safety, and happiness.
Dr.
Jiang Junyi from Taoyuan is concerned about you.

Reply Date: 2021/08/02

More Info


Nighttime headaches can be a perplexing and distressing issue, especially when they disrupt sleep and lead to daytime fatigue. In your case, the onset of headaches following vaccination raises several important considerations.
Firstly, it is essential to recognize that headaches can be a common side effect of vaccinations. Vaccines, including those for COVID-19, can trigger immune responses that may result in symptoms such as headaches, muscle aches, and fatigue. These symptoms typically resolve within a few days, but in some individuals, they may persist longer. The fact that your headaches began the day after vaccination and continued for a week suggests that they could be related to the immune response initiated by the vaccine.

The specific nature of your headaches—localized to the right temple area and described as a tight sensation—could indicate a tension-type headache or even a migraine. Tension-type headaches are often associated with muscle tightness and stress, while migraines can be triggered by various factors, including hormonal changes, stress, and even certain foods. The fact that your headaches worsen at night and can wake you from sleep is particularly noteworthy. Nighttime headaches can be caused by several factors, including:
1. Tension and Stress: As the day progresses, accumulated stress and muscle tension can lead to headaches. If you are experiencing anxiety or stress, this could contribute to nighttime headaches.

2. Sleep Position: Poor sleep posture can lead to muscle strain in the neck and shoulders, which may trigger headaches. If you sleep in a position that puts strain on your neck, it could lead to tension headaches.

3. Sleep Disorders: Conditions such as sleep apnea can lead to fragmented sleep and headaches upon waking. If you snore or experience pauses in breathing during sleep, it may be worth discussing with a healthcare provider.

4. Medication Effects: If you are taking medications for anxiety or sleep, the timing and effects of these medications could also play a role in your headaches. Some medications can lead to rebound headaches if taken too frequently.

5. Caffeine Withdrawal: If you consume caffeine during the day and do not have it in the evening, withdrawal symptoms could manifest as headaches at night.

Regarding your concern about whether nighttime headaches indicate a serious neurological condition, it is important to note that while persistent headaches can be a sign of underlying issues, the absence of other neurological symptoms (such as weakness, speech difficulties, or visual changes) is reassuring. However, if your headaches continue or worsen, or if you develop new symptoms, it is crucial to seek further evaluation from a healthcare provider, preferably a neurologist. They may recommend imaging studies, such as an MRI, to rule out any serious conditions.

In summary, while your headaches may be related to the vaccination and subsequent immune response, factors such as stress, sleep posture, and potential sleep disorders should also be considered. Keeping a headache diary to track the timing, duration, and triggers of your headaches can be helpful for your healthcare provider in determining the best course of action. If your symptoms persist, do not hesitate to seek further medical advice to ensure that you receive appropriate care and management for your headaches.

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