Managing Liver Fibrosis: Essential Steps for B Hepatitis Carriers - Gastroenterology and Hepatology

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Liver fibrosis issues?


Hello, doctor.
I am a carrier of hepatitis B and have been regularly monitored at a gastroenterology clinic, undergoing liver function tests and abdominal ultrasounds every six months.
In recent years, all my tests have shown no abnormalities.
Last month, during my follow-up, the doctor informed me that there is some fibrosis in my liver (with liver function and alpha-fetoprotein levels both normal).
I was advised to rest more.
What proactive measures can I take to avoid progressing towards the three stages of liver disease?

Xiao Zhuang, 40~49 year old female. Ask Date: 2021/08/10

Dr. Chen Shidian reply Gastroenterology and Hepatology


Maintaining a regular lifestyle and diet, along with monitoring changes in the condition and managing it with medication, can lead to a positive future!

Reply Date: 2021/08/10

More Info


Managing liver fibrosis, especially for individuals who are carriers of Hepatitis B, is a critical aspect of maintaining liver health and preventing progression to more severe liver diseases such as cirrhosis and liver cancer. Here are some essential steps and considerations for managing liver fibrosis effectively:

Regular Monitoring and Follow-Up
1. Regular Check-Ups: As a Hepatitis B carrier, it is crucial to have regular follow-ups with a hepatologist or a gastroenterologist. This typically includes blood tests to monitor liver function (such as ALT and AST levels), viral load (HBV DNA), and liver imaging (like ultrasound or FibroScan) to assess the degree of fibrosis.

2. Fibrosis Assessment: Since you mentioned that your doctor indicated some fibrosis, it’s essential to understand the stage of fibrosis. FibroScan is a non-invasive method to estimate liver stiffness, which correlates with fibrosis. Regular assessments can help track any changes over time.


Lifestyle Modifications
3. Diet and Nutrition: A balanced diet is vital for liver health. Focus on a diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid high-fat, high-sugar, and processed foods, as these can exacerbate liver issues. If you have fatty liver, weight management is particularly important.

4. Exercise: Regular physical activity can help improve liver health and reduce the risk of further fibrosis. Aim for at least 150 minutes of moderate aerobic exercise each week, along with strength training exercises.

5. Avoid Alcohol and Toxins: Alcohol can significantly worsen liver damage, so it is advisable to avoid it entirely. Additionally, be cautious with medications and supplements, as some can be hepatotoxic.


Medical Management
6. Antiviral Therapy: Depending on your viral load and liver condition, your doctor may recommend antiviral therapy. Current antiviral medications, such as tenofovir or entecavir, can effectively suppress the virus and reduce liver inflammation, which may help prevent further fibrosis.

7. Monitoring for Complications: Regular screening for liver cancer (hepatocellular carcinoma) is crucial, especially if you have significant fibrosis. This typically involves ultrasound and serum alpha-fetoprotein (AFP) testing every six months.


Addressing Co-Morbidities
8. Manage Other Health Conditions: Conditions such as diabetes, hypertension, and hyperlipidemia can exacerbate liver issues. Managing these conditions through lifestyle changes and medications can help protect your liver.

9. Vaccinations: Ensure you are vaccinated against hepatitis A and other preventable diseases, as infections can further compromise liver health.


Psychological Support
10. Mental Health: Living with a chronic condition can be stressful. Consider seeking support from mental health professionals or support groups for chronic illness to help manage any anxiety or depression related to your health.


Conclusion
In summary, managing liver fibrosis as a Hepatitis B carrier involves a combination of regular monitoring, lifestyle modifications, medical management, and addressing any co-existing health conditions. It’s essential to work closely with your healthcare provider to tailor a management plan that suits your specific needs and to stay proactive about your liver health. By taking these steps, you can significantly reduce the risk of progression to cirrhosis or liver cancer and maintain a healthier life. Always consult with your healthcare provider before making any changes to your treatment or lifestyle.

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