Chronic Urticaria: When to Seek Further Medical Help - Internal Medicine

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Urticaria issues?


About a month ago, I started experiencing unexplained itching all over my body (my diet and daily routine have not changed).
If I scratch, it becomes red but does not develop into hives.
I have since seen two different doctors who diagnosed me with mild urticaria and prescribed medication.
However, after taking the medication for two days, my condition is still fluctuating.
Is this consistent with urticaria? Is it normal to still experience itching sometimes even after taking the medication for two days? Given that the urticaria has persisted for a month, should I go to the hospital for further evaluation? Thank you.

Xiao Wen, 30~39 year old female. Ask Date: 2021/08/13

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your message.
Urticaria needs to be visually assessed, so if you suspect it is urticaria, it would be helpful to take a photo of the appearance during an outbreak for the physician's evaluation.
Additionally, even with medication, some cases of urticaria may still occur despite treatment; therefore, if outbreaks continue after medication, it is important to return for a follow-up appointment so the treating physician can adjust your medication.
Lastly, if urticaria recurs for a month, it is advisable to seek further evaluation at a hospital.
In cases of prolonged urticaria, besides the possibility of allergies, immune dysfunction should also be considered, which may require a more extensive range of tests.
The Allergy, Immunology, and Rheumatology Department at Changhua Hospital, Ministry of Health and Welfare, is here to support you.

Reply Date: 2021/08/13

More Info


Chronic urticaria, commonly known as hives, is a condition characterized by the presence of itchy welts on the skin that can vary in size and can appear anywhere on the body. It can be triggered by various factors, including allergens, stress, medications, and even certain foods. In your case, it seems that you have been experiencing generalized itching without the typical wheals or hives, which can sometimes complicate the diagnosis.

Given your symptoms of generalized itching and the diagnosis of low-grade urticaria from two different physicians, it is essential to understand a few key points about chronic urticaria and when to seek further medical help.

1. Understanding Chronic Urticaria: Chronic urticaria is defined as hives that persist for six weeks or longer. It can be idiopathic (without a known cause) or triggered by specific factors. The itching you experience can be quite bothersome and may lead to scratching, which can cause redness and irritation of the skin. The absence of wheals does not rule out urticaria, as some patients may experience only itching and redness without the typical raised welts.

2. Medication Response: You mentioned that you have been taking medication for two days, but your symptoms are still inconsistent. It is not uncommon for antihistamines, which are typically prescribed for urticaria, to take some time to show their full effect. However, if you are still experiencing significant itching after two days of treatment, it may indicate that the current medication is not adequately controlling your symptoms. It is essential to follow up with your healthcare provider to discuss your ongoing symptoms and the effectiveness of the treatment.

3. When to Seek Further Medical Help: If your symptoms persist for more than a month, it is advisable to seek further medical evaluation. This is particularly important if:
- The itching is severe and affecting your quality of life.

- You develop new symptoms, such as swelling of the face, lips, or throat, which could indicate an allergic reaction.

- You experience difficulty breathing or swallowing.

- The rash or itching worsens despite treatment.

- You have concerns about the underlying cause of your symptoms, especially if they are not responding to standard treatments.

4. Potential Investigations: In cases of chronic urticaria, further investigations may be warranted to identify potential triggers or underlying conditions. This could include blood tests, allergy testing, or even a referral to a dermatologist or allergist for specialized care.
5. Lifestyle Considerations: While awaiting further evaluation, consider keeping a diary of your symptoms, noting any potential triggers, such as foods, medications, or stressors. This information can be valuable for your healthcare provider in determining the best course of action.

In conclusion, while it is possible that your symptoms are related to chronic urticaria, the persistence of your symptoms and the lack of improvement with medication warrant further evaluation. It is essential to communicate openly with your healthcare provider about your symptoms and any concerns you may have. Seeking further medical help can lead to a more tailored treatment approach and help alleviate your discomfort.

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