Persistent Cough: Causes and Treatment Options - Pulmonology

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Coughing for a long time?


Hello Doctor: I have been coughing since I caught a cold around October last year, and it lasted for more than a month.
I later visited a pulmonologist who performed an X-ray and pulmonary function tests.
Initially, I was prescribed cough suppressants and expectorants, but my cough did not improve.
The doctor then prescribed a dry powder inhaler, which provided significant relief immediately.
The doctor mentioned that I might have asthma.
I have been using the inhaler for the past 7 to 8 months with good control, but last month I suddenly started coughing again, and it has been almost a month.
The doctor switched my medication to a bronchodilator, and I am on the second day of using it, but there doesn't seem to be much improvement.
My family thinks my persistent cough might be caused by gastroesophageal reflux disease (GERD).
Could you please advise what might be the underlying cause of my symptoms?

Han, 20~29 year old female. Ask Date: 2021/08/20

Dr. Yang Wenda reply Pulmonology


Hello Han: From the previous use of inhalers, there has been improvement, and the physician's diagnosis of asthma seems to be correct.
However, asthma patients can still experience acute exacerbations due to factors such as colds, exposure to allergens (like dust mites or pollen), significant temperature changes, or gastroesophageal reflux.
It is recommended to continue using bronchodilators along with medications to suppress gastric acid, which should help improve the condition.
As for whether there is gastroesophageal reflux, an endoscopy is necessary for diagnosis.

Reply Date: 2021/08/20

More Info


Persistent cough can be a frustrating and challenging symptom to manage, especially when it lingers for months. Based on your description, it seems that you have experienced a prolonged cough following an initial respiratory infection, which has now evolved into a more complex situation involving potential asthma and possibly gastroesophageal reflux disease (GERD).


Understanding the Causes of Persistent Cough
1. Post-Infectious Cough: After a viral respiratory infection, it is common for some individuals to experience a lingering cough. This is often due to airway hyperreactivity, where the airways remain sensitive and reactive even after the infection has resolved. This can lead to a chronic cough that may last for weeks or even months.

2. Asthma: Your history of using a bronchodilator (the inhaler you mentioned) suggests that asthma may be a contributing factor. Asthma is characterized by inflammation and narrowing of the airways, leading to symptoms such as wheezing, shortness of breath, and coughing, particularly at night or early in the morning. The fact that you experienced significant improvement with the inhaler indicates that asthma could be a primary cause of your cough.

3. Gastroesophageal Reflux Disease (GERD): Your family’s suggestion that your cough might be related to GERD is also worth considering. GERD can cause chronic cough due to acid irritating the throat and airways, leading to a reflexive cough. Symptoms of GERD often include heartburn, regurgitation, and a sour taste in the mouth, but some individuals may only present with a chronic cough.

4. Allergic Rhinitis or Sinusitis: Allergies can also contribute to a persistent cough. Post-nasal drip, where mucus drips down the back of the throat, can trigger coughing. If you have a history of allergies, this could be a factor as well.

5. Chronic Bronchitis: If you are a smoker or have been exposed to irritants, chronic bronchitis could be a consideration. This condition is characterized by a productive cough that lasts for at least three months in two consecutive years.


Treatment Options
1. Asthma Management: Since you have been prescribed inhalers, it is crucial to continue using them as directed. If your symptoms are not well-controlled, you may need to follow up with your healthcare provider to adjust your asthma management plan. This could include the addition of inhaled corticosteroids or other medications.

2. GERD Treatment: If GERD is suspected, lifestyle modifications such as avoiding trigger foods (spicy, fatty foods, caffeine), eating smaller meals, and not lying down immediately after eating can be beneficial. Over-the-counter antacids or prescription medications like proton pump inhibitors (PPIs) may also help alleviate symptoms.

3. Allergy Management: If allergies are contributing to your cough, antihistamines or nasal corticosteroids may be helpful. Identifying and avoiding allergens can also reduce symptoms.

4. Cough Suppressants and Expectorants: Depending on the nature of your cough (dry vs. productive), your doctor may recommend cough suppressants or expectorants to help manage symptoms.

5. Follow-Up Care: Since your cough has persisted despite treatment, it is essential to maintain open communication with your healthcare provider. Further evaluation, such as allergy testing or a referral to a gastroenterologist for GERD evaluation, may be warranted.


Conclusion
In summary, your persistent cough could be attributed to a combination of factors, including asthma, potential GERD, and possibly post-infectious changes. It is essential to work closely with your healthcare provider to determine the most appropriate treatment plan tailored to your specific symptoms and underlying causes. Regular follow-up and adjustments to your treatment regimen may be necessary to achieve optimal control of your cough and improve your quality of life.

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