Chronic Cough: Causes and Treatments for Persistent Symptoms - Pulmonology

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Coughing for a long time?


Hello Doctor: I have been coughing since I caught a cold around October last year, and it lasted for more than a month.
I later visited a pulmonologist who performed an X-ray and pulmonary function tests.
Initially, I was prescribed cough suppressants and expectorants, but my cough did not improve.
Eventually, the doctor prescribed a dry powder inhaler (Rhinocort), which provided significant relief immediately.
The doctor mentioned that I might have asthma.
I have been using the inhaler for the past 7 to 8 months with good control.
However, last month, I suddenly started coughing again, and it has been almost a month.
The doctor switched my medication to a bronchodilator, and I am on the second day of using it, but there hasn't been much improvement.
My family thinks my persistent cough might be caused by gastroesophageal reflux disease (GERD).
Could you please advise what might be the underlying cause of my symptoms?

Han, 20~29 year old female. Ask Date: 2021/08/22

Dr. Yang Wenda reply Pulmonology


Hello Han: Based on the previous improvement with the inhaler, the physician's diagnosis of asthma seems to be correct.
However, asthma patients can still experience acute exacerbations due to factors such as colds, exposure to allergens (like dust mites or pollen), significant temperature changes, or gastroesophageal reflux.
It is recommended to continue using the bronchodilator along with medications to suppress gastric acid, which should help improve the condition.
As for the possibility of gastroesophageal reflux, a gastroscopy is necessary for diagnosis.

Reply Date: 2021/08/22

More Info


Chronic cough can be a frustrating and debilitating symptom, often stemming from various underlying conditions. Based on your description, it seems that your cough has persisted for several months, with an initial onset following a respiratory infection. You have undergone evaluations, including chest X-rays and pulmonary function tests, which have ruled out significant lung pathology. Your experience with medications such as a cough suppressant and expectorant, followed by the use of an inhaler for asthma, suggests that your cough may be multifactorial.


Possible Causes of Chronic Cough
1. Asthma: Given that you have been prescribed a bronchodilator (the inhaler), it is likely that your healthcare provider suspects asthma as a contributing factor. Asthma can cause chronic cough, especially if it is not well-controlled. Symptoms may include wheezing, shortness of breath, and chest tightness, which can be exacerbated by allergens, exercise, or respiratory infections.

2. Postnasal Drip: Chronic cough can also result from postnasal drip, where mucus from the nasal passages drips down the back of the throat, triggering the cough reflex. This condition is often associated with allergies or sinusitis and can be exacerbated by irritants like smoke or strong odors.

3. Gastroesophageal Reflux Disease (GERD): Your family's suggestion of GERD is worth considering. Acid reflux can irritate the throat and airways, leading to a chronic cough. Symptoms may include heartburn, regurgitation, or a sour taste in the mouth, particularly after meals or when lying down.

4. Chronic Bronchitis: If you have a history of smoking or exposure to irritants, chronic bronchitis could be a possibility. This condition is characterized by a productive cough that lasts for at least three months in two consecutive years.

5. Medication Side Effects: Some medications, particularly ACE inhibitors used for hypertension, can cause a chronic cough as a side effect. If you are on such medications, it may be worth discussing alternatives with your doctor.


Treatment and Management
1. Asthma Management: If asthma is confirmed, ensure you are using your inhaler correctly and regularly. A step-up in therapy may be necessary if symptoms persist. This could include the addition of inhaled corticosteroids or a combination inhaler that includes both a corticosteroid and a long-acting bronchodilator.

2. Addressing Postnasal Drip: If postnasal drip is suspected, consider using saline nasal sprays or rinses to keep the nasal passages moist. Antihistamines or nasal corticosteroids may also help reduce inflammation and mucus production.

3. GERD Management: If GERD is a concern, lifestyle modifications such as avoiding large meals, not lying down immediately after eating, and elevating the head of your bed can be beneficial. Over-the-counter antacids or prescription medications may also be necessary.

4. Follow-Up Care: Since your cough has persisted despite treatment, it is crucial to follow up with your healthcare provider. They may consider further evaluations, such as allergy testing or a trial of proton pump inhibitors for GERD, to determine the underlying cause of your symptoms.

5. Lifestyle Modifications: Avoid known irritants such as tobacco smoke, strong odors, and allergens. Staying hydrated and using a humidifier can also help soothe the airways.


Conclusion
Chronic cough can arise from various causes, and it often requires a comprehensive approach to diagnosis and management. Given your history and the treatments you've tried, it would be beneficial to have an open discussion with your healthcare provider about your ongoing symptoms. They can help tailor a treatment plan that addresses the specific causes of your cough, whether it be asthma, GERD, or another condition. Remember, effective management often involves a combination of medication, lifestyle changes, and regular follow-up to monitor your progress.

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