Chronic Cough: Causes and Treatment Options - Pulmonology

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Coughing for a long time?


Hello Doctor: I have been coughing since I caught a cold around October last year, and it lasted for more than a month.
I later visited a pulmonologist who performed an X-ray and pulmonary function tests.
Initially, I took cough suppressants and expectorants, but my cough did not improve.
Eventually, the doctor prescribed a dry powder inhaler, which significantly improved my condition.
The doctor mentioned that I might have asthma.
I used the inhaler for the next 7 to 8 months, and my symptoms were well controlled.
However, last month, I suddenly started coughing again, and it has been almost a month.
The doctor switched my medication to a bronchodilator, and I am on the second day of using it, but there hasn't been much improvement.
My family thinks my cough might be caused by gastroesophageal reflux disease (GERD).
Could you please advise what might be the underlying cause of my symptoms?

Han, 20~29 year old female. Ask Date: 2021/08/23

Dr. Yang Wenda reply Pulmonology


Hello Han: Based on previous improvements with the inhaler, the physician's diagnosis of asthma seems accurate.
However, asthma patients can still experience acute exacerbations due to factors such as colds, exposure to allergens (like dust mites or pollen), significant temperature changes, or gastroesophageal reflux.
It is recommended to continue using the bronchodilator along with medications to suppress gastric acid, which should help improve the condition.
As for the possibility of gastroesophageal reflux, a gastroscopy is necessary for diagnosis.

Reply Date: 2021/08/23

More Info


Chronic cough can be a frustrating and debilitating condition, especially when it persists for an extended period, as you've described. Based on your symptoms and medical history, there are several potential causes for your chronic cough, and understanding these can help guide appropriate treatment options.


Possible Causes of Chronic Cough
1. Asthma: Given that you were diagnosed with asthma and have been using a bronchodilator (the inhaler), it is possible that your cough is related to asthma exacerbations. Asthma can cause inflammation and narrowing of the airways, leading to symptoms such as wheezing, shortness of breath, and chronic cough, particularly at night or early in the morning.

2. Gastroesophageal Reflux Disease (GERD): Your family’s suggestion that your cough may be due to gastroesophageal reflux disease (GERD) is also worth considering. GERD can cause acid to flow back into the esophagus, which may irritate the throat and trigger a cough reflex. This is often worse when lying down, which can lead to nighttime coughing.

3. Postnasal Drip: Chronic cough can also be caused by postnasal drip, where mucus from the sinuses drips down the back of the throat, leading to irritation and coughing. This is often associated with allergies or sinus infections.

4. Chronic Bronchitis: If you have a history of smoking or exposure to irritants, chronic bronchitis could be a factor. This condition is characterized by a persistent cough that produces mucus.

5. Infections: While less likely if you have been evaluated and treated, lingering infections such as a chronic bronchial infection or even a lingering effect from a past viral infection (like COVID-19) could contribute to ongoing cough.


Treatment Options
1. Asthma Management: If asthma is confirmed as a cause, ensure that you are using your inhaler correctly and consistently. It may also be beneficial to have a follow-up appointment with your healthcare provider to reassess your asthma management plan. Sometimes, additional medications such as inhaled corticosteroids or leukotriene modifiers may be necessary.

2. GERD Treatment: If GERD is suspected, lifestyle modifications such as avoiding trigger foods (spicy, fatty, or acidic foods), not eating close to bedtime, and elevating the head of your bed may help. Over-the-counter antacids or proton pump inhibitors (PPIs) could also be considered, but it’s best to consult with a healthcare provider before starting any new medication.

3. Postnasal Drip Management: If postnasal drip is contributing to your cough, using saline nasal sprays, antihistamines, or nasal corticosteroids may provide relief. Staying hydrated and using a humidifier can also help thin mucus.

4. Further Evaluation: Since your cough has persisted despite treatment, it may be beneficial to revisit your healthcare provider for further evaluation. This could include additional tests such as a CT scan of the chest, allergy testing, or a referral to a gastroenterologist if GERD is suspected.

5. Lifestyle Modifications: Avoiding known irritants (like smoke or strong odors), staying hydrated, and practicing good respiratory hygiene can also help manage symptoms.


Conclusion
Chronic cough can arise from various underlying conditions, and it often requires a multifaceted approach to treatment. Given your history of asthma and the potential for GERD, it would be prudent to work closely with your healthcare provider to determine the most appropriate management plan. Keeping a symptom diary, noting when your cough worsens and any associated symptoms, can also provide valuable information for your healthcare provider. Remember, persistent symptoms warrant further investigation to ensure that any underlying issues are addressed effectively.

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