Small Blisters at the Corners of Your Mouth - Dermatology

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Why do I have small blisters at the corners of my mouth?


Hmm...
there are small blisters appearing at the corners of the mouth.
What could be causing this? Is it a viral infection?

A-Dai, 20~29 year old female. Ask Date: 2000/12/21

Dr. Zheng Lizhen reply Dermatology


Based on your description, it is likely a case of herpes simplex.
Herpes simplex is a viral infection caused by a filterable virus and is prone to recurrence.
Be careful not to rupture the blisters on your own, as this may lead to secondary bacterial infections.
There are antiviral medications available for oral or topical use, but due to health insurance regulations, coverage is only provided for individuals who meet certain specific criteria (such as those with compromised immune systems or critical corneal conditions, etc.); others will need to pay out of pocket.

Reply Date: 2000/12/21

More Info


Small blisters at the corners of your mouth can be concerning, and it's important to understand the potential causes and implications. These blisters, often referred to as vesicles, can arise from a variety of conditions, and while some may be benign, others could indicate a viral infection or other underlying issues.

One common cause of small blisters in the oral cavity, particularly at the corners of the mouth, is herpes simplex virus (HSV). This virus is known for causing cold sores, which typically appear as painful, fluid-filled blisters. The initial outbreak may be accompanied by symptoms such as itching, burning, or tingling sensations before the blisters appear. If you have a history of cold sores or have been exposed to someone with HSV, this could be a likely explanation for the blisters you are experiencing.

Another possibility is angular cheilitis, which is characterized by inflammation and cracking at the corners of the mouth. This condition can lead to the formation of small blisters or sores and is often caused by a combination of factors, including fungal infections (like Candida), bacterial infections, or even nutritional deficiencies (such as vitamin B12 or iron deficiency). Angular cheilitis can be exacerbated by habits such as licking the lips, which can introduce moisture and irritants to the area.

Additionally, if you have been under stress or have experienced changes in your immune system, this could also contribute to the development of blisters. Stress can weaken the immune response, making you more susceptible to infections, including those caused by viruses like HSV.

In terms of treatment, if the blisters are indeed caused by HSV, antiviral medications can be effective in reducing the severity and duration of outbreaks. Over-the-counter topical treatments may also provide relief from discomfort. For angular cheilitis, maintaining good oral hygiene, applying barrier creams, and addressing any underlying nutritional deficiencies can help alleviate symptoms.

It's important to monitor the blisters closely. If they persist, worsen, or are accompanied by other symptoms such as fever, swollen lymph nodes, or significant pain, it is advisable to seek medical attention. A healthcare provider can perform a thorough examination, possibly including swabs or blood tests, to determine the exact cause of the blisters and recommend appropriate treatment.

In summary, small blisters at the corners of your mouth can be caused by various factors, including viral infections like HSV, angular cheilitis, or other irritations. Understanding the underlying cause is crucial for effective management, so if you have concerns, don't hesitate to consult a healthcare professional for a proper diagnosis and treatment plan.

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