Rubella IgG Levels: Do You Need the Vaccine Before Pregnancy?

Measles screening index?

Hello Doctor: I had a preconception check-up in August this year, and the test report showed my Rubella IgG level at 0.170, while the reference value is >10.0 (+) IU/mL.
The report did not indicate any abnormalities, and the gynecologist did not mention anything unusual at the time.
After going home and reviewing the information online, I am still unclear whether I should receive the rubella vaccine.
Thank you!

Cai Nüshi, 30~39 year old female. Ask Date: 2021/08/27

Dr. Zhang Kunmin reply Obstetrics and Gynecology

Hello, based on your description, if the test values and units are correct, I recommend that you discuss with the interpreting physician to confirm whether you need to receive the vaccine.
Thank you! Wishing you peace and health.
Dr.
Zhang

Reply Date: 2021/08/27

More Info

When it comes to understanding your Rubella IgG levels and whether you need to receive the rubella vaccine before pregnancy, it's essential to interpret the results correctly. Your reported Rubella IgG level of 0.170 IU/mL is significantly below the reference value of >10.0 IU/mL, which indicates that you are likely not immune to rubella. In fact, a level below 10 IU/mL typically suggests that you have no protective antibodies against the rubella virus.

Rubella, also known as German measles, is a viral infection that can have serious consequences during pregnancy, particularly in the first trimester. If a pregnant woman contracts rubella, it can lead to congenital rubella syndrome (CRS), which can cause severe birth defects, including heart problems, hearing impairments, and developmental delays in the baby. Therefore, ensuring immunity to rubella before becoming pregnant is crucial.

Given your low IgG level, it is advisable to discuss with your healthcare provider the possibility of receiving the rubella vaccine before attempting to conceive. The rubella vaccine is a live attenuated vaccine, and it is recommended that women of childbearing age ensure they are immune to rubella before pregnancy. If you receive the vaccine, it is generally advised to wait at least one month before trying to conceive to ensure that the vaccine has had time to take effect and to avoid any potential risks to a developing fetus.

In summary, based on your Rubella IgG level of 0.170 IU/mL, it is highly recommended that you consider getting the rubella vaccine before becoming pregnant. This will help protect both you and your future baby from the risks associated with rubella infection during pregnancy. It is always best to have a thorough discussion with your healthcare provider to make an informed decision tailored to your specific health needs and circumstances.

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