Autonomic Nervous System Disorders: Symptoms and Medication Guidance - Psychiatry

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Symptoms of autonomic nervous system dysfunction and medication consultation?


Hello, Doctor: I was previously diagnosed with autonomic nervous system dysfunction and took Escitalopram for about a year before discontinuing it as per my doctor's advice.
During the medication period, I experienced almost no side effects; however, a few months after stopping, I began to experience discomfort symptoms again.
I consulted a different doctor who prescribed Imipramine, one tablet daily.
I have been on this medication for two weeks without interruption.
Initially, I did not experience any side effects, and I gradually noticed an improvement in my tension symptoms.
However, five days ago, I started experiencing dizziness and shortness of breath.
I initially thought it might be premenstrual syndrome, but these symptoms have persisted without relief.
The dizziness feels different from my previous autonomic nervous system dysfunction; it resembles a floating sensation, imbalance, and lightheadedness (not vertigo), accompanied by decreased appetite, shortness of breath, rapid heartbeat (which measures normal), bloating, and gastroesophageal reflux.
The more I focus on these symptoms, the more intense the discomfort seems to become.
A few days ago, due to feeling very unwell, I took one tablet each of Uliban and Xinkang before bed, but there was no improvement in my symptoms.
Since my follow-up appointment is still a week away, I would like to ask how to interpret this situation.
Is it a side effect of the medication? Is the medication ineffective? Or is it simply not yet taking effect? Should I schedule an earlier appointment, or do you recommend observing for a few more days? Thank you!

A, 20~29 year old female. Ask Date: 2021/09/02

Dr. Zhang Gengjia reply Psychiatry


Dear Sir/Madam,
From your letter, it is clear that you are experiencing discomfort and distress due to both autonomic nervous system dysregulation and anxiety disorder.

1.
Facing an uncertain future, anxiety disorders are common in modern society.
This is a chronic condition that requires long-term treatment for recovery.

2.
Continuing medical treatment will certainly help your condition, but due to individual differences in physiology, it may take time to identify the most suitable medication.
Please be patient and cooperate with your physician.

3.
In terms of medication treatment alone, each primary medication requires 4 to 6 weeks to assess its effectiveness.
I recommend that if you experience any discomfort, you should note the duration and frequency of these symptoms.
You can discuss them thoroughly with your physician during your next appointment, as some symptoms may be related to the original condition, while others may be side effects of the medication.
Our clinic is open for consultations from Monday to Friday, both in the morning and afternoon.
I suggest you consider visiting the clinic for a personal evaluation of your symptoms, so we can collaboratively determine the best course of action for you.
Wishing you mental and physical well-being.
Sincerely,
Dr.
Chang Geng-Jia
Department of Psychiatry

Reply Date: 2021/09/02

More Info


Understanding autonomic nervous system (ANS) disorders can be quite complex, especially when symptoms overlap with various psychological and physical health issues. Based on your description, it seems you have been navigating a challenging path with your diagnosis of autonomic nervous system dysfunction, and your experiences with medications like Escitalopram and Imipramine have raised several concerns.

The autonomic nervous system is responsible for regulating involuntary bodily functions, including heart rate, blood pressure, respiration, and digestion. When this system is out of balance, it can lead to a variety of symptoms, including dizziness, palpitations, gastrointestinal issues, and feelings of anxiety or tension. Your symptoms of dizziness, breathlessness, and gastrointestinal discomfort, alongside the history of anxiety and autonomic dysfunction, suggest that your body may still be struggling to find equilibrium.

The medications you have been prescribed—Escitalopram, an SSRI (selective serotonin reuptake inhibitor), and Imipramine, a tricyclic antidepressant—are commonly used to treat anxiety and depressive disorders. While they can be effective, they also come with potential side effects. The symptoms you are experiencing now, such as dizziness and a sensation of imbalance, could indeed be related to the medication. However, they could also stem from the underlying autonomic dysfunction or even be a manifestation of anxiety itself.

It's important to note that the onset of new symptoms after starting a new medication can sometimes indicate that the body is adjusting to the treatment. In your case, since you mentioned that the symptoms began about five days ago, it is possible that your body is still adapting to Imipramine. However, the persistence of these symptoms warrants careful consideration.

Here are a few points to consider regarding your current situation:
1. Medication Side Effects: Both Imipramine and other medications you mentioned can cause dizziness and gastrointestinal symptoms. It’s essential to monitor how long these symptoms last and whether they improve as your body adjusts to the medication.

2. Underlying Conditions: Given your history of autonomic dysfunction, it’s possible that your symptoms are a continuation of that condition rather than solely a side effect of the medication. Conditions like anxiety can exacerbate feelings of dizziness and gastrointestinal distress, creating a cycle that can be difficult to break.

3. Psychological Factors: Anxiety can amplify physical sensations, leading to increased awareness of symptoms like dizziness and breathlessness. This heightened awareness can create a feedback loop where anxiety worsens physical symptoms, which in turn increases anxiety.

4. Need for Follow-Up: Since your symptoms have changed and are causing you distress, it would be prudent to reach out to your healthcare provider sooner rather than later. They can assess whether a dosage adjustment or a different medication might be necessary. Additionally, they may want to rule out any other potential causes for your symptoms.

5. Self-Care Strategies: While waiting for your appointment, consider engaging in relaxation techniques such as deep breathing exercises, mindfulness, or gentle physical activity, which can help alleviate anxiety and improve your overall sense of well-being.

In conclusion, your symptoms may be a combination of medication side effects, the underlying autonomic dysfunction, and anxiety. It is crucial to maintain open communication with your healthcare provider about your symptoms and any changes you experience. They can provide the best guidance on whether to adjust your treatment plan or explore other therapeutic options. Remember, managing autonomic nervous system disorders often requires a comprehensive approach that includes both medical treatment and lifestyle modifications.

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