Can Skin Medication Affect Birth Control Pill Effectiveness? - Obstetrics and Gynecology

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During the "break" period of taking pre-exposure prophylaxis (PrEP), I took skin medication?


Hello, Doctor.
I had been taking oral contraceptives for several months and decided to pause in May of this year.
I recently started taking my first pack of "Yueji" again at the beginning of August, and I took the last pill of the first pack on August 27.
My period started as expected on the afternoon of August 31.
However, I have recently experienced skin allergies (dermatitis).
I visited a dermatologist on August 31, and the doctor prescribed me 5 or 6 pills to take after breakfast and dinner.
Therefore, I took the medication prescribed by the dermatologist from the evening of August 31 until the morning of September 3.
I am supposed to start my second pack of oral contraceptives today, September 4.
I would like to ask if taking the skin medication for three days during my menstrual period (which is also the pause period for the contraceptive) will affect the effectiveness of the second pack of oral contraceptives.
Additionally, during September, can I engage in unprotected sexual intercourse? (The earliest I could engage in unprotected sex would be September 15).
Thank you for your assistance!

Miss Lin, 20~29 year old female. Ask Date: 2021/09/04

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it generally does not have an impact.
Birth control pills should still be started on the fifth day of your menstrual period.
Wishing you good health.

Reply Date: 2021/09/04

More Info


When it comes to the interaction between skin medications and birth control pills, it's essential to understand how different medications can affect hormonal contraceptives. Generally, most topical medications, including those used for skin conditions like dermatitis or eczema, do not significantly impact the effectiveness of birth control pills. This is because the hormones in birth control pills are absorbed systemically through the gastrointestinal tract, while topical medications are applied directly to the skin and have minimal systemic absorption.

In your case, since you took skin medication for a few days during your menstrual cycle and are now considering starting your second pack of birth control pills, you should be in a safe position. The skin medications you took are unlikely to interfere with the effectiveness of your birth control pills. However, it is always wise to consult with your healthcare provider about any specific medications you are taking, especially if they are systemic (oral) medications, as some can potentially interact with hormonal contraceptives.

Regarding your concern about engaging in unprotected sexual intercourse, it is generally recommended to wait until you have taken your birth control pills consistently for at least seven days after starting a new pack. Since you mentioned that you will be starting your second pack on September 4 and plan to wait until September 15 for unprotected sex, this aligns well with the typical guidance. By that time, if you have taken your pills as directed, you should be adequately protected against pregnancy.

It's also important to note that if you experience any side effects from the skin medication or have concerns about your skin condition, you should follow up with your dermatologist. They can provide guidance on managing your skin issues while ensuring that your birth control remains effective.

In summary, the skin medications you took are unlikely to affect the effectiveness of your birth control pills. You can resume unprotected sexual activity after ensuring that you have taken your birth control pills consistently for the recommended period. Always keep open communication with your healthcare providers about any medications you are taking and any concerns you may have regarding your reproductive health.

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Hello, it should not be the case. Wishing you good health.

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