Hepatitis B antigen and antibody issues?
Hello Doctor: In August, I had blood tests for arthritis at the rheumatology department, and the physician also conducted tests for viral hepatitis.
The report indicated that my hepatitis B surface antigen antibody level was 1.28, which exceeds the normal range.
The doctor advised that I should follow up with a hepatologist.
Since I undergo annual health check-ups, and all my hepatitis serology values were normal six months ago, and my spouse is also normal with no carrier status, I am certain that I have not had any blood exposure with others, so is it possible to contract the hepatitis B virus without any known risk factors? Additionally, I currently have the virus but had normal hepatitis B tests during both of my pregnancies.
Do my children need to undergo additional testing? I have already scheduled a follow-up with a specialist, but this situation has come as a surprise, and I need some psychological reassurance.
I hope you can help clarify these concerns.
Thank you for your response.
LIN, 30~39 year old female. Ask Date: 2021/09/04
Dr. Lin Minghui reply Gastroenterology and Hepatology
Hello: Regarding the issue of hepatitis B antigen and antibody.
If there is hepatitis B surface antigen but no hepatitis B antibodies, the individual is considered a carrier.
Liver function tests may be normal, so regular monitoring of liver function, AFP (alpha-fetoprotein), and abdominal ultrasound is necessary.
Hepatitis B is transmitted through blood and bodily fluids.
It is also possible that a person was previously infected and, due to certain factors such as immunosuppression or medication, the virus has been reactivated.
Currently, pregnant mothers are being tested for hepatitis B.
The child has received the vaccine.
At one and a half years old, it is possible to test for the presence of hepatitis B antibodies.
Carriers of hepatitis B need to be monitored regularly.
Wishing you peace and health! Sincerely, Dr.
Lin Ming-Hui, Attending Physician, Department of Gastroenterology, Taoyuan Hospital, Ministry of Health and Welfare.
Reply Date: 2021/09/04
More Info
Understanding Hepatitis B Antigen and Antibody Results: What You Need to Know
Hello! Thank you for reaching out with your concerns regarding your recent Hepatitis B test results. It’s understandable to feel anxious when faced with unexpected medical findings, especially when it comes to something as serious as Hepatitis B. Let’s break down your situation and clarify what your results mean.
From your report, it appears that your Hepatitis B surface antigen (HBsAg) level is elevated at 1.28, which indicates that you may have an active Hepatitis B infection. HBsAg is a protein on the surface of the Hepatitis B virus; its presence in the blood suggests that the virus is replicating and that you are potentially infectious. The normal range for HBsAg is typically below 1.0 IU/ml, so your result indicates that further evaluation is necessary.
You mentioned that your previous tests were normal and that you have no known risk factors for Hepatitis B, such as tattoos or blood exposure. It is indeed possible to contract Hepatitis B through other means, including sexual contact or from an infected mother during childbirth, even if you are not aware of any direct exposure. Hepatitis B can also be transmitted through sharing personal items like razors or toothbrushes, although these routes are less common.
Regarding your children, it is crucial to monitor their Hepatitis B status, especially if you are a carrier of the virus. The Centers for Disease Control and Prevention (CDC) recommends that all infants born to mothers who are Hepatitis B positive receive the Hepatitis B vaccine and hepatitis B immune globulin (HBIG) within 12 hours of birth. This is to prevent transmission of the virus from mother to child. If your children were born when you were tested as negative, they may not need immediate testing, but it is wise to consult with your pediatrician about their vaccination status and whether they should be tested for Hepatitis B.
Since you are already scheduled for a follow-up with a gastroenterologist or hepatologist, this is a positive step. They will likely conduct further tests, including Hepatitis B viral load (HBV DNA) testing, liver function tests, and possibly a liver ultrasound to assess the health of your liver. These tests will help determine the extent of the infection and whether treatment is necessary.
In terms of psychological support, it’s important to acknowledge your feelings of anxiety and uncertainty. Consider discussing your concerns with a mental health professional or joining a support group for individuals dealing with chronic health conditions. Connecting with others who have similar experiences can provide comfort and valuable insights.
In summary, your elevated HBsAg level indicates that you may have an active Hepatitis B infection, and it is essential to follow up with a specialist for further evaluation and management. Ensure that your children are monitored for Hepatitis B, especially if there is any risk of transmission. Lastly, don’t hesitate to seek emotional support as you navigate this situation. Your health and well-being are paramount, and being proactive about your care is the best approach.
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